Palladium-catalyzed benzylic substitution of benzyl carbonates with phosphorus nucleophiles

Yusuke Makida, Kazumi Usui, Satoshi Ueno, Ryoichi Kuwano

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A wide range of benzyl carbonates reacted with dimethyl phosphonate or diphenylphosphine oxide in the presence of the palladium catalyst, [Pd(η3-allyl)Cl]2DPEphos, to give dimethyl benzylphosphonates and benzyldiphenylphosphine oxides in high yields. The catalytic phosphonylation was applied to the one-pot synthesis of alkenes from the benzyl esters.

Original languageEnglish
Pages (from-to)1814-1817
Number of pages4
JournalChemistry Letters
Volume46
Issue number12
DOIs
Publication statusPublished - Jan 1 2017

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Nucleophiles
Carbonates
Palladium
Alkenes
Phosphorus
Oxides
Esters
Substitution reactions
Catalysts
triphenylphosphine oxide
dimethyl hydrogen phosphite

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

Palladium-catalyzed benzylic substitution of benzyl carbonates with phosphorus nucleophiles. / Makida, Yusuke; Usui, Kazumi; Ueno, Satoshi; Kuwano, Ryoichi.

In: Chemistry Letters, Vol. 46, No. 12, 01.01.2017, p. 1814-1817.

Research output: Contribution to journalArticle

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