Palladium-Catalyzed Decarboxylation of Benzyl Fluorobenzoates

Yusuke Makida, Yasutaka Matsumoto, Ryoichi Kuwano

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The decarboxylation of benzyl fluorobenzoates has been developed by using the palladium catalyst prepared in situ from Pd(η 3 -allyl)Cp and bulky monophosphine ligand XPhos. The catalytic reaction afforded a range of fluorinated diarylmethanes in good yields with broad functional-group compatibility. The substrates were readily synthesized by condensation of the corresponding benzoic acid with benzyl alcohol. Therefore, the transformation is formally regarded as a cross-coupling reaction between fluorine-containing benzoic acids and benzyl alcohols.

Original languageEnglish
Pages (from-to)2573-2576
Number of pages4
Issue number19
Publication statusPublished - Dec 1 2017

All Science Journal Classification (ASJC) codes

  • Organic Chemistry


Dive into the research topics of 'Palladium-Catalyzed Decarboxylation of Benzyl Fluorobenzoates'. Together they form a unique fingerprint.

Cite this