Palladium-catalyzed oxidation of cyclohexanones to conjugated enones using molecular oxygen

Makoto Tokunaga, Saki Harada, Tetsuo Iwasawa, Yasushi Obora, Yasushi Tsuji

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Oxidation of cyclohexanones into conjugated enones with molecular oxygen as oxidant was achieved by palladium catalysts. A catalyst system consists of 1 mol % Pd(OCOCF3)2 and 5,5′-dimethyl-2,2′-bipyridine accomplished maximum 84% yield for the oxidation of cyclohexanone and 51-78% yields for 4-substituted-cyclohexanones.

Original languageEnglish
Pages (from-to)6860-6862
Number of pages3
JournalTetrahedron Letters
Volume48
Issue number39
DOIs
Publication statusPublished - Sep 24 2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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