Pancreatic abscess caused by Corynebacterium coyleae mimicking malignant neoplasm

Masashi Taguchi, Shoichiro Nishikawa, Hidehiko Matsuoka, Ryoichi Narita, Shintaro Abe, Kazumasa Fukuda, Hiroshi Miyamoto, Hatsumi Taniguchi, Makoto Otsuki

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A 50-year-old female was referred to our hospital because of postprandial epigastric pain and pancreatic head mass. On admission, an elastic hard mass with tenderness was palpable in the epigastric region. Laboratory findings showed no abnormalities, except for a slightly elevated C-reactive protein value and iron deficiency anemia. Serum levels of pancreatic enzymes and tumor markers were also within the reference range. Computed tomography (CT) demonstrated a 5-cm heterogenous mass at the head of the pancreas. Angiography showed that gastroduodenal artery was transformed and narrowed by the mass. Smooth stenosis of portal vein was also observed. Fusion CT-positron emission tomography with 2-deoxy-2-[F]fluoro-D-glucose demonstrated a focus of increased uptake in the pancreatic head mass. We suspected the mass of malignancy but, surprisingly, tumor size was gradually decreased without any therapies. Biopsy specimens from the mass of the pancreas showed marked inflammatory cell infiltration and marked interstitial fibrosis without malignant cells. Thereafter, we could isolate Corynebacterium coyleae from the biopsy specimen. We diagnosed the mass as a pancreatic abscess caused by C. coyleae and started with the intravenous antibiotics therapy. Subsequent follow-up CT and ultrasonography showed dramatic improvement in pancreatic mass.We present here a case of pancreatic abscess which was difficult to differentiate from malignant lesion by various imaging studies. Moreover, we could culture and identify C. coyleae which had never been reported to be the source of pancreatic abscess.

Original languageEnglish
Pages (from-to)425-429
Number of pages5
JournalPancreas
Volume33
Issue number4
DOIs
Publication statusPublished - Nov 1 2006
Externally publishedYes

Fingerprint

Corynebacterium
Abscess
Pancreas
Tomography
Biopsy
Neoplasms
Iron-Deficiency Anemias
Fluorodeoxyglucose F18
Tumor Biomarkers
Portal Vein
C-Reactive Protein
Headache
Ultrasonography
Angiography
Pathologic Constriction
Reference Values
Fibrosis
Arteries
Anti-Bacterial Agents
Enzymes

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

Cite this

Taguchi, M., Nishikawa, S., Matsuoka, H., Narita, R., Abe, S., Fukuda, K., ... Otsuki, M. (2006). Pancreatic abscess caused by Corynebacterium coyleae mimicking malignant neoplasm. Pancreas, 33(4), 425-429. https://doi.org/10.1097/01.mpa.0000236730.08747.69

Pancreatic abscess caused by Corynebacterium coyleae mimicking malignant neoplasm. / Taguchi, Masashi; Nishikawa, Shoichiro; Matsuoka, Hidehiko; Narita, Ryoichi; Abe, Shintaro; Fukuda, Kazumasa; Miyamoto, Hiroshi; Taniguchi, Hatsumi; Otsuki, Makoto.

In: Pancreas, Vol. 33, No. 4, 01.11.2006, p. 425-429.

Research output: Contribution to journalArticle

Taguchi, M, Nishikawa, S, Matsuoka, H, Narita, R, Abe, S, Fukuda, K, Miyamoto, H, Taniguchi, H & Otsuki, M 2006, 'Pancreatic abscess caused by Corynebacterium coyleae mimicking malignant neoplasm', Pancreas, vol. 33, no. 4, pp. 425-429. https://doi.org/10.1097/01.mpa.0000236730.08747.69
Taguchi M, Nishikawa S, Matsuoka H, Narita R, Abe S, Fukuda K et al. Pancreatic abscess caused by Corynebacterium coyleae mimicking malignant neoplasm. Pancreas. 2006 Nov 1;33(4):425-429. https://doi.org/10.1097/01.mpa.0000236730.08747.69
Taguchi, Masashi ; Nishikawa, Shoichiro ; Matsuoka, Hidehiko ; Narita, Ryoichi ; Abe, Shintaro ; Fukuda, Kazumasa ; Miyamoto, Hiroshi ; Taniguchi, Hatsumi ; Otsuki, Makoto. / Pancreatic abscess caused by Corynebacterium coyleae mimicking malignant neoplasm. In: Pancreas. 2006 ; Vol. 33, No. 4. pp. 425-429.
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