Pannexin 3, a gap junction protein, regulates chondrocyte differentiation in part through hemichannel activity

Tsutomu Iwamoto, Mariko Ono, Makiko Arakaki, Takashi Nakamura, Aya Yamada, Satoshi Fukumoto

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Gap junctional communications play a crucial role for organogenesis including cartilage development. Pannexin 3 (Panx3) belongs to the new member of the gap junction pannexin family. However, the expression and function of Panx3 have not been cleared. Here, we demonstrate that Panx3 is expressed in cartridge, and regulates chondrocyte differentiation in vitro cell culture. Our observations indicate that Panx3 plays a crucial role for the differentiation of chondrocyte, and suggest that Panx3 is a key molecule for cartilage development.

Original languageEnglish
Title of host publicationInterface Oral Health Science 2011
PublisherSpringer Japan
Pages346-348
Number of pages3
ISBN (Electronic)9784431540700
ISBN (Print)9784431540694
DOIs
Publication statusPublished - Jan 1 2012

Fingerprint

Connexins
Chondrocytes
Cartilage
Organogenesis
Gap Junctions
Cell Culture Techniques
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

Iwamoto, T., Ono, M., Arakaki, M., Nakamura, T., Yamada, A., & Fukumoto, S. (2012). Pannexin 3, a gap junction protein, regulates chondrocyte differentiation in part through hemichannel activity. In Interface Oral Health Science 2011 (pp. 346-348). Springer Japan. https://doi.org/10.1007/978-4-431-54070-0_100

Pannexin 3, a gap junction protein, regulates chondrocyte differentiation in part through hemichannel activity. / Iwamoto, Tsutomu; Ono, Mariko; Arakaki, Makiko; Nakamura, Takashi; Yamada, Aya; Fukumoto, Satoshi.

Interface Oral Health Science 2011. Springer Japan, 2012. p. 346-348.

Research output: Chapter in Book/Report/Conference proceedingChapter

Iwamoto, T, Ono, M, Arakaki, M, Nakamura, T, Yamada, A & Fukumoto, S 2012, Pannexin 3, a gap junction protein, regulates chondrocyte differentiation in part through hemichannel activity. in Interface Oral Health Science 2011. Springer Japan, pp. 346-348. https://doi.org/10.1007/978-4-431-54070-0_100
Iwamoto T, Ono M, Arakaki M, Nakamura T, Yamada A, Fukumoto S. Pannexin 3, a gap junction protein, regulates chondrocyte differentiation in part through hemichannel activity. In Interface Oral Health Science 2011. Springer Japan. 2012. p. 346-348 https://doi.org/10.1007/978-4-431-54070-0_100
Iwamoto, Tsutomu ; Ono, Mariko ; Arakaki, Makiko ; Nakamura, Takashi ; Yamada, Aya ; Fukumoto, Satoshi. / Pannexin 3, a gap junction protein, regulates chondrocyte differentiation in part through hemichannel activity. Interface Oral Health Science 2011. Springer Japan, 2012. pp. 346-348
@inbook{a2c34cea3d544d43b58c33f33f51d6c2,
title = "Pannexin 3, a gap junction protein, regulates chondrocyte differentiation in part through hemichannel activity",
abstract = "Gap junctional communications play a crucial role for organogenesis including cartilage development. Pannexin 3 (Panx3) belongs to the new member of the gap junction pannexin family. However, the expression and function of Panx3 have not been cleared. Here, we demonstrate that Panx3 is expressed in cartridge, and regulates chondrocyte differentiation in vitro cell culture. Our observations indicate that Panx3 plays a crucial role for the differentiation of chondrocyte, and suggest that Panx3 is a key molecule for cartilage development.",
author = "Tsutomu Iwamoto and Mariko Ono and Makiko Arakaki and Takashi Nakamura and Aya Yamada and Satoshi Fukumoto",
year = "2012",
month = "1",
day = "1",
doi = "10.1007/978-4-431-54070-0_100",
language = "English",
isbn = "9784431540694",
pages = "346--348",
booktitle = "Interface Oral Health Science 2011",
publisher = "Springer Japan",
address = "Japan",

}

TY - CHAP

T1 - Pannexin 3, a gap junction protein, regulates chondrocyte differentiation in part through hemichannel activity

AU - Iwamoto, Tsutomu

AU - Ono, Mariko

AU - Arakaki, Makiko

AU - Nakamura, Takashi

AU - Yamada, Aya

AU - Fukumoto, Satoshi

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Gap junctional communications play a crucial role for organogenesis including cartilage development. Pannexin 3 (Panx3) belongs to the new member of the gap junction pannexin family. However, the expression and function of Panx3 have not been cleared. Here, we demonstrate that Panx3 is expressed in cartridge, and regulates chondrocyte differentiation in vitro cell culture. Our observations indicate that Panx3 plays a crucial role for the differentiation of chondrocyte, and suggest that Panx3 is a key molecule for cartilage development.

AB - Gap junctional communications play a crucial role for organogenesis including cartilage development. Pannexin 3 (Panx3) belongs to the new member of the gap junction pannexin family. However, the expression and function of Panx3 have not been cleared. Here, we demonstrate that Panx3 is expressed in cartridge, and regulates chondrocyte differentiation in vitro cell culture. Our observations indicate that Panx3 plays a crucial role for the differentiation of chondrocyte, and suggest that Panx3 is a key molecule for cartilage development.

UR - http://www.scopus.com/inward/record.url?scp=84957031872&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84957031872&partnerID=8YFLogxK

U2 - 10.1007/978-4-431-54070-0_100

DO - 10.1007/978-4-431-54070-0_100

M3 - Chapter

AN - SCOPUS:84957031872

SN - 9784431540694

SP - 346

EP - 348

BT - Interface Oral Health Science 2011

PB - Springer Japan

ER -