Paradoxical lateralization of parasagittal spikes revealed by back averaging of EEG and MEG in a case with epilepsia partialis continua

Ayame Oishi, Shozo Tobimatsu, Hirofumi Ochi, Yasumasa Ohyagi, Takamichi Kubota, Takayuki Taniwaki, Tomoya Yamamoto, Hirokazu Furuya, Jun-Ichi Kira

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Our aim was to localize the generator site of parasagittal epileptiform discharges in a patient with epilepsia partialis continua (EPC) in the right leg. We examined a 32-year-old woman with EPC whose conventional EEG did not show any epileptic discharge. We performed the jerk-locked back averaging (JLA) of EEG and magnetoencephalography (MEG) to localize the dipole source of sharp transients. The myoclonic discharges in the right soleus muscle were used as a trigger pulse. JLA revealed consistent EEG and MEG sharp transients that coincided consistently and constantly preceded the myoclonic jerks. JLA of EEG demonstrated sharp waves paradoxically distributed over the vertex and right hemisphere. However, the estimated dipoles of MEG were localized in a restricted area in the primary leg motor area in the left hemisphere, which was closely located in the abnormal lesion on the brain MRI. JLA of MEG is considered to be a useful non-invasive method for localizing the epileptogenic area in EPC even when paradoxical lateralization of electroencephalographic discharges was noted.

Original languageEnglish
Pages (from-to)151-155
Number of pages5
JournalJournal of the Neurological Sciences
Volume193
Issue number2
DOIs
Publication statusPublished - Jan 15 2002

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Epilepsia Partialis Continua
Magnetoencephalography
Electroencephalography
Leg
Myoclonus
Motor Cortex
Skeletal Muscle
Brain

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Paradoxical lateralization of parasagittal spikes revealed by back averaging of EEG and MEG in a case with epilepsia partialis continua. / Oishi, Ayame; Tobimatsu, Shozo; Ochi, Hirofumi; Ohyagi, Yasumasa; Kubota, Takamichi; Taniwaki, Takayuki; Yamamoto, Tomoya; Furuya, Hirokazu; Kira, Jun-Ichi.

In: Journal of the Neurological Sciences, Vol. 193, No. 2, 15.01.2002, p. 151-155.

Research output: Contribution to journalArticle

Oishi, Ayame ; Tobimatsu, Shozo ; Ochi, Hirofumi ; Ohyagi, Yasumasa ; Kubota, Takamichi ; Taniwaki, Takayuki ; Yamamoto, Tomoya ; Furuya, Hirokazu ; Kira, Jun-Ichi. / Paradoxical lateralization of parasagittal spikes revealed by back averaging of EEG and MEG in a case with epilepsia partialis continua. In: Journal of the Neurological Sciences. 2002 ; Vol. 193, No. 2. pp. 151-155.
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