Abstract
We apply Lagrangian particle method combined with the level-set method to model morphogenesis of budding yeast on the subcellular level. We model the biochemical reactions, anisotropic diffusion, membrane-cytoplasmic transport of proteins and introduction of new membrane material (exocytosis) that occur on the plasma membrane. Exocytosis results in protrusion of the membrane surface. Hence, to model these phenomena we need to solve a system of reaction-diffusion-advection equations on the evolving surface.
| Original language | English |
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| Title of host publication | Particle-Based Methods III |
| Subtitle of host publication | Fundamentals and Applications - Proceedings of the 3rd International Conference on Particle-based MethodsFundamentals and Applications, Particles 2013 |
| Pages | 145-152 |
| Number of pages | 8 |
| Publication status | Published - Dec 1 2013 |
| Externally published | Yes |
| Event | 3rd International Conference on Particle-Based Methods Fundamentals and Applications, Particles 2013 - Stuttgart, Germany Duration: Sep 18 2013 → Sep 20 2013 |
Publication series
| Name | Particle-Based Methods III: Fundamentals and Applications - Proceedings of the 3rd International Conference on Particle-based MethodsFundamentals and Applications, Particles 2013 |
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Other
| Other | 3rd International Conference on Particle-Based Methods Fundamentals and Applications, Particles 2013 |
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| Country | Germany |
| City | Stuttgart |
| Period | 9/18/13 → 9/20/13 |
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All Science Journal Classification (ASJC) codes
- Atomic and Molecular Physics, and Optics
Cite this
Leda, M., Okada, S., Bi, E., Barral, Y., & Goryachev, A. B. (2013). Particle-Based model of cellular morphogenesis in budding yeast. In Particle-Based Methods III: Fundamentals and Applications - Proceedings of the 3rd International Conference on Particle-based MethodsFundamentals and Applications, Particles 2013 (pp. 145-152). (Particle-Based Methods III: Fundamentals and Applications - Proceedings of the 3rd International Conference on Particle-based MethodsFundamentals and Applications, Particles 2013).