Abstract
It has been established that oxidative stress plays a crucial role in the development and progression of vascular diseases. Besides the mitochondria, the NADPH oxidase/Nox family proteins are now thought to be important origins of the reactive oxygen species that underlie various vascular disease states, such as hypertension, atherosclerosis, angiogenesis, and ischemia/reperfusion injury. This review summarizes the basis of vascular Nox proteins and discusses their pathophysiological roles in the vascular system.
| Original language | English |
|---|---|
| Pages (from-to) | 1791-1800 |
| Number of pages | 10 |
| Journal | Circulation Journal |
| Volume | 75 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 1 2011 |
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All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine
Cite this
Pathophysiological roles of NADPH oxidase/Nox family proteins in the vascular system review and perspective. / Ago, Tetsuro; Kuroda, Junya; Kamouchi, Masahiro; Sadoshima, Junichi; Kitazono, Takanari.
In: Circulation Journal, Vol. 75, No. 8, 01.08.2011, p. 1791-1800.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Pathophysiological roles of NADPH oxidase/Nox family proteins in the vascular system review and perspective
AU - Ago, Tetsuro
AU - Kuroda, Junya
AU - Kamouchi, Masahiro
AU - Sadoshima, Junichi
AU - Kitazono, Takanari
PY - 2011/8/1
Y1 - 2011/8/1
N2 - It has been established that oxidative stress plays a crucial role in the development and progression of vascular diseases. Besides the mitochondria, the NADPH oxidase/Nox family proteins are now thought to be important origins of the reactive oxygen species that underlie various vascular disease states, such as hypertension, atherosclerosis, angiogenesis, and ischemia/reperfusion injury. This review summarizes the basis of vascular Nox proteins and discusses their pathophysiological roles in the vascular system.
AB - It has been established that oxidative stress plays a crucial role in the development and progression of vascular diseases. Besides the mitochondria, the NADPH oxidase/Nox family proteins are now thought to be important origins of the reactive oxygen species that underlie various vascular disease states, such as hypertension, atherosclerosis, angiogenesis, and ischemia/reperfusion injury. This review summarizes the basis of vascular Nox proteins and discusses their pathophysiological roles in the vascular system.
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UR - http://www.scopus.com/inward/citedby.url?scp=79960792993&partnerID=8YFLogxK
U2 - 10.1253/circj.CJ-11-0388
DO - 10.1253/circj.CJ-11-0388
M3 - Review article
C2 - 21673456
AN - SCOPUS:79960792993
VL - 75
SP - 1791
EP - 1800
JO - Circulation Journal
JF - Circulation Journal
SN - 1346-9843
IS - 8
ER -