Patterned Adsorption of Protein onto a Carbohydrate Monolayer Immobilized on Si

Naoto Shirahata; Tetsu Yonezawa; Yoshiko Miura; Kazukiyo Kobayashi; Kunihito Koumoto

doi:10.1021/la0349020

Patterned Adsorption of Protein onto a Carbohydrate Monolayer Immobilized on Si

Naoto Shirahata, Tetsu Yonezawa, Yoshiko Miura, Kazukiyo Kobayashi, Kunihito Koumoto

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

We propose a technique for fabricating a carbohydrate-terminated monolayer (CM) surface, which is extremely flat at the angstrom level. The CM was immobilized onto a Si surface by Si-C covalent bond. Specific adsorption of the protein molecule from a contacting solution was observed on the CM area of a patterned CM substrate surface, while its nonspecific adsorption was observed on the Si-O area.

Original language	English
Pages (from-to)	9107-9109
Number of pages	3
Journal	Langmuir
Volume	19
Issue number	22
DOIs	https://doi.org/10.1021/la0349020
Publication status	Published - Oct 28 2003
Externally published	Yes

All Science Journal Classification (ASJC) codes

Materials Science(all)
Condensed Matter Physics
Surfaces and Interfaces
Spectroscopy
Electrochemistry

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10.1021/la0349020

Cite this

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abstract = "We propose a technique for fabricating a carbohydrate-terminated monolayer (CM) surface, which is extremely flat at the angstrom level. The CM was immobilized onto a Si surface by Si-C covalent bond. Specific adsorption of the protein molecule from a contacting solution was observed on the CM area of a patterned CM substrate surface, while its nonspecific adsorption was observed on the Si-O area.",

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AU - Shirahata, Naoto

AU - Yonezawa, Tetsu

AU - Miura, Yoshiko

AU - Kobayashi, Kazukiyo

AU - Koumoto, Kunihito

PY - 2003/10/28

Y1 - 2003/10/28

N2 - We propose a technique for fabricating a carbohydrate-terminated monolayer (CM) surface, which is extremely flat at the angstrom level. The CM was immobilized onto a Si surface by Si-C covalent bond. Specific adsorption of the protein molecule from a contacting solution was observed on the CM area of a patterned CM substrate surface, while its nonspecific adsorption was observed on the Si-O area.

AB - We propose a technique for fabricating a carbohydrate-terminated monolayer (CM) surface, which is extremely flat at the angstrom level. The CM was immobilized onto a Si surface by Si-C covalent bond. Specific adsorption of the protein molecule from a contacting solution was observed on the CM area of a patterned CM substrate surface, while its nonspecific adsorption was observed on the Si-O area.

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Patterned Adsorption of Protein onto a Carbohydrate Monolayer Immobilized on Si

Abstract

All Science Journal Classification (ASJC) codes

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