Patterned Adsorption of Protein onto a Carbohydrate Monolayer Immobilized on Si

Naoto Shirahata, Tetsu Yonezawa, Yoshiko Miura, Kazukiyo Kobayashi, Kunihito Koumoto

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37 Citations (Scopus)

Abstract

We propose a technique for fabricating a carbohydrate-terminated monolayer (CM) surface, which is extremely flat at the angstrom level. The CM was immobilized onto a Si surface by Si-C covalent bond. Specific adsorption of the protein molecule from a contacting solution was observed on the CM area of a patterned CM substrate surface, while its nonspecific adsorption was observed on the Si-O area.

Original languageEnglish
Pages (from-to)9107-9109
Number of pages3
JournalLangmuir
Volume19
Issue number22
DOIs
Publication statusPublished - Oct 28 2003
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

Cite this

Shirahata, N., Yonezawa, T., Miura, Y., Kobayashi, K., & Koumoto, K. (2003). Patterned Adsorption of Protein onto a Carbohydrate Monolayer Immobilized on Si. Langmuir, 19(22), 9107-9109. https://doi.org/10.1021/la0349020