PEG-silica-modified gold nanorods that retain their optical properties in tumor tissues

Yasuyuki Akiyama, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Gold nanorods modified with polyethylene glycol (PEG) chains via Au-S bonds form aggregates, and their absorption spectra broaden in tumor tissues. In contrast, the gold nanorods modified here via the crosslinking of PEG chains on the silica shell on gold nanorods showed enhanced permeability and retention effects and retained the optical properties of the original gold nanorods in tumor tissues.

Original languageEnglish
Pages (from-to)2071-2080
Number of pages10
JournalJournal of Biomaterials Science, Polymer Edition
Volume24
Issue number18
DOIs
Publication statusPublished - Dec 1 2013

Fingerprint

Nanotubes
Nanorods
Silicon Dioxide
Gold
Polyethylene glycols
Tumors
Optical properties
Silica
Tissue
Neoplasms
Crosslinking
Absorption spectra
Permeability

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

Cite this

PEG-silica-modified gold nanorods that retain their optical properties in tumor tissues. / Akiyama, Yasuyuki; Niidome, Yasuro; Mori, Takeshi; Katayama, Yoshiki; Niidome, Takuro.

In: Journal of Biomaterials Science, Polymer Edition, Vol. 24, No. 18, 01.12.2013, p. 2071-2080.

Research output: Contribution to journalArticle

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