PEG-silica-modified gold nanorods that retain their optical properties in tumor tissues

Yasuyuki Akiyama, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Gold nanorods modified with polyethylene glycol (PEG) chains via Au-S bonds form aggregates, and their absorption spectra broaden in tumor tissues. In contrast, the gold nanorods modified here via the crosslinking of PEG chains on the silica shell on gold nanorods showed enhanced permeability and retention effects and retained the optical properties of the original gold nanorods in tumor tissues.

Original languageEnglish
Pages (from-to)2071-2080
Number of pages10
JournalJournal of Biomaterials Science, Polymer Edition
Volume24
Issue number18
DOIs
Publication statusPublished - Dec 1 2013

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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