Peptide synthesis by surfactant-chymotrypsin complexes in organic media

Kojiro Abe, Toshiyuki Kawazoe, Shin Ya Okazaki, Masahiro Goto, Fumiyuki Nakashio

    Research output: Contribution to journalArticlepeer-review

    6 Citations (Scopus)

    Abstract

    Peptide synthesis by surfactant-chymotrypsin (CT) complexes was performed in organic media containing 1%-8% (v/v) water. The CT complex exhibited a higher enzymatic activity than native CT. The control of the water content in the reaction media has a crucial effect on the enzymatic activity. The maximum conversion (57%) for the peptide synthesis by the surfactant-CT complex was obtained at 4% water content.

    Original languageEnglish
    Pages (from-to)25-29
    Number of pages5
    JournalBiotechnology Techniques
    Volume11
    Issue number1
    DOIs
    Publication statusPublished - Jan 1 1997

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Applied Microbiology and Biotechnology

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