Performance of extracorporeally adjustable ventricular assist device inflow cannula

Akira Shiose; Hyun Il Kim; Tohru Takaseya; Mariko Kobayashi; Masako Fujiki; Ji Feng Chen; Ryan Klatte; Shengqiang Gao; Alex L. Massiello; Diyar Saeed; Kiyotaka Fukamachi

doi:10.1016/j.athoracsur.2010.06.081

Performance of extracorporeally adjustable ventricular assist device inflow cannula

Akira Shiose, Hyun Il Kim, Tohru Takaseya, Mariko Kobayashi, Masako Fujiki, Ji Feng Chen, Ryan Klatte, Shengqiang Gao, Alex L. Massiello, Diyar Saeed, Kiyotaka Fukamachi

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Purpose: This study evaluated the feasibility and efficacy of a newly developed adjustable left ventricular assist device inflow cannula in a short-term calf model. Description: In this inflow cannula, the angle between the cannula body and the inflow cannula tip can be altered extracorporeally by manipulating 2 externalized cables connected to the cannula. The cannula tip is adjustable in any plane to a maximum of ±15 degrees. Evaluation: After initial prototyping in 4 calf cadavers, a Cleveland Heart left ventricular assist device was implanted with the adjustable inflow cannula placed in the left ventricular apex and the outlet to the descending aorta. Under hypovolemic conditions, the angle of the cannula tip could be changed to induce varying degrees of ventricular suction and then eliminate it, as evidenced by recorded pump and native left ventricular flows. Epicardial echocardiography and fluoroscopy in the closed-chest condition documented extracorporeal adjustments of the inflow cannula position. Conclusions: This extracorporeally adjustable inflow cannula was effective in preventing or controlling left ventricular suction.

Original language	English
Pages (from-to)	1682-1687
Number of pages	6
Journal	Annals of Thoracic Surgery
Volume	90
Issue number	5
DOIs	https://doi.org/10.1016/j.athoracsur.2010.06.081
Publication status	Published - Nov 2010
Externally published	Yes

All Science Journal Classification (ASJC) codes

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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10.1016/j.athoracsur.2010.06.081

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@article{d335e1f11c0a483db5ca1dc2f00e1d29,

title = "Performance of extracorporeally adjustable ventricular assist device inflow cannula",

abstract = "Purpose: This study evaluated the feasibility and efficacy of a newly developed adjustable left ventricular assist device inflow cannula in a short-term calf model. Description: In this inflow cannula, the angle between the cannula body and the inflow cannula tip can be altered extracorporeally by manipulating 2 externalized cables connected to the cannula. The cannula tip is adjustable in any plane to a maximum of ±15 degrees. Evaluation: After initial prototyping in 4 calf cadavers, a Cleveland Heart left ventricular assist device was implanted with the adjustable inflow cannula placed in the left ventricular apex and the outlet to the descending aorta. Under hypovolemic conditions, the angle of the cannula tip could be changed to induce varying degrees of ventricular suction and then eliminate it, as evidenced by recorded pump and native left ventricular flows. Epicardial echocardiography and fluoroscopy in the closed-chest condition documented extracorporeal adjustments of the inflow cannula position. Conclusions: This extracorporeally adjustable inflow cannula was effective in preventing or controlling left ventricular suction.",

author = "Akira Shiose and Kim, {Hyun Il} and Tohru Takaseya and Mariko Kobayashi and Masako Fujiki and Chen, {Ji Feng} and Ryan Klatte and Shengqiang Gao and Massiello, {Alex L.} and Diyar Saeed and Kiyotaka Fukamachi",

note = "Funding Information: This work was supported by the Innovation Validation Fund from Cleveland Clinic to Dr Fukamachi. We thank Bard Inc for the polyester velour fabric material.",

year = "2010",

month = nov,

doi = "10.1016/j.athoracsur.2010.06.081",

language = "English",

volume = "90",

pages = "1682--1687",

journal = "Annals of Thoracic Surgery",

issn = "0003-4975",

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T1 - Performance of extracorporeally adjustable ventricular assist device inflow cannula

AU - Shiose, Akira

AU - Kim, Hyun Il

AU - Takaseya, Tohru

AU - Kobayashi, Mariko

AU - Fujiki, Masako

AU - Chen, Ji Feng

AU - Klatte, Ryan

AU - Gao, Shengqiang

AU - Massiello, Alex L.

AU - Saeed, Diyar

AU - Fukamachi, Kiyotaka

N1 - Funding Information: This work was supported by the Innovation Validation Fund from Cleveland Clinic to Dr Fukamachi. We thank Bard Inc for the polyester velour fabric material.

PY - 2010/11

Y1 - 2010/11

N2 - Purpose: This study evaluated the feasibility and efficacy of a newly developed adjustable left ventricular assist device inflow cannula in a short-term calf model. Description: In this inflow cannula, the angle between the cannula body and the inflow cannula tip can be altered extracorporeally by manipulating 2 externalized cables connected to the cannula. The cannula tip is adjustable in any plane to a maximum of ±15 degrees. Evaluation: After initial prototyping in 4 calf cadavers, a Cleveland Heart left ventricular assist device was implanted with the adjustable inflow cannula placed in the left ventricular apex and the outlet to the descending aorta. Under hypovolemic conditions, the angle of the cannula tip could be changed to induce varying degrees of ventricular suction and then eliminate it, as evidenced by recorded pump and native left ventricular flows. Epicardial echocardiography and fluoroscopy in the closed-chest condition documented extracorporeal adjustments of the inflow cannula position. Conclusions: This extracorporeally adjustable inflow cannula was effective in preventing or controlling left ventricular suction.

AB - Purpose: This study evaluated the feasibility and efficacy of a newly developed adjustable left ventricular assist device inflow cannula in a short-term calf model. Description: In this inflow cannula, the angle between the cannula body and the inflow cannula tip can be altered extracorporeally by manipulating 2 externalized cables connected to the cannula. The cannula tip is adjustable in any plane to a maximum of ±15 degrees. Evaluation: After initial prototyping in 4 calf cadavers, a Cleveland Heart left ventricular assist device was implanted with the adjustable inflow cannula placed in the left ventricular apex and the outlet to the descending aorta. Under hypovolemic conditions, the angle of the cannula tip could be changed to induce varying degrees of ventricular suction and then eliminate it, as evidenced by recorded pump and native left ventricular flows. Epicardial echocardiography and fluoroscopy in the closed-chest condition documented extracorporeal adjustments of the inflow cannula position. Conclusions: This extracorporeally adjustable inflow cannula was effective in preventing or controlling left ventricular suction.

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JO - Annals of Thoracic Surgery

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Performance of extracorporeally adjustable ventricular assist device inflow cannula

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