Peripheral expansion of ωδT cell receptor‐positive cells in a patient with Crohn's disease

TOSHIRO HARA, TADASHI MATSUMOTO, YUMI MIZUNO, MARI NISHIZAKI, KOHJI UEDA, MAKOTO MOTOOKA, NOBUHIRO KIMURA, KAZUO OSHIMI, SHOICHI OHGA, YASUNOBU YOSHIKAI

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Abstract

A13 year old boy with Crohn's disease had a prominent expansion (over 40%) of ωδT cell receptor‐positive cells (ωδT cells) in the peripheral blood. The ωδT cells were gradually decreased from 48 to 22% in 18 months. Anti‐ωδT cell receptor‐triggered cytotoxicity was evident at onset and after 1 year. The significance of peripheral expansion of ωδT cells in a patient with Crohn's disease is discussed. 1993 Japan Pediatric Society

Original languageEnglish
Pages (from-to)45-48
Number of pages4
JournalPediatrics International
Volume35
Issue number1
DOIs
Publication statusPublished - Feb 1993

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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