Peripheral T cell lymphoma with a high titer of proteinase-3-antineutrophil cytoplasmic antibodies that resembled Wegener's granulomatosis

Tsuyoshi Shirai, Reiko Takahashi, Yumi Tajima, Katsura Kohata, Joji Yamamoto, Hiroshi Fujii, Naruhiko Takasawa, Kenichi Ishizawa, Ryo Ichinohasama, Tomonori Ishii, Hideo Harigae

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5 Citations (Scopus)


Here, we present a 54-year-old man with proptosis and swelling below the left eyelid. Laboratory findings showed high levels of PR3-ANCA and histological examination of the first biopsy revealed acute inflammation. Together with the findings of MRI, a diagnosis of WG was made. However, the disease progressed rapidly and histological examination of the second biopsy revealed infiltration of neoplastic T lymphocytes with aberrant loss of CD7. A final diagnosis of peripheral T cell lymphoma, not otherwise specified (WHO) was made, and complete remission was achieved by chemotherapy. This is a very rare case of T cell lymphoma with a high titer of PR3-ANCA.

Original languageEnglish
Pages (from-to)2041-2045
Number of pages5
JournalInternal Medicine
Issue number23
Publication statusPublished - Dec 1 2009


All Science Journal Classification (ASJC) codes

  • Internal Medicine

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