Personality and colorectal cancer: The Fukuoka Colorectal Cancer Study

Jun Nagano, Suminori Kono, Kengo Toyomura, Tetsuya Mizoue, Guang Yin, Ryuichi Mibu, Masao Tanaka, Yoshihiro Kakeji, Yoshihiko Maehara, Takeshi Okamura, Koji Ikejiri, Kitaroh Futami, Yohichi Yasunami, Takafumi Maekawa, Kenji Takenaka, Hitoshi Ichimiya, Nobutoshi Imaizumi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective: Although personality factors, especially emotional suppression and loss-hopelessness, have been linked to the occurrence and progression of cancer, little is reported specifically on colorectal cancer. It has also been claimed that a "hysterical" personality characterized by exaggerated emotional expressions, egocentricity and ambivalent connection may be protective from cancer. This community-based case-control study examined whether personality factors relevant to emotional suppression or loss-hopelessness are associated with an increased risk of colorectal cancer, and whether factors related to the hysterical personality are associated with a decreased risk. Methods: The stress inventory (SI), a self-administered questionnaire to assess the possible disease-prone and other relevant personalities in Japanese, was completed by 497 patients with newly diagnosed colorectal cancer and 809 controls randomly selected in the Fukuoka area of Japan. Results: After controlling for age, sex and residence using a logistic regression model, none of the SI scales relevant to emotional suppression ("unfulfilled needs for acceptance", "altruism", "rationalizing conflicts/frustrations") or loss-hopelessness ("low sense of control", "object-dependence/loss", "object-dependence/ happiness") was related to colorectal cancer. On the other hand, two scales representing elements of the hysterical personality, "object-dependence/ambivalence" and "egoism" were protectively associated with risk. Additional adjustment for body-mass index and lifestyle factors did not materially change these associations. Conclusions: Although personalities relevant to the emotional suppression or loss-hopelessness may not be a risk factor for colorectal cancer in the Japanese population, ambivalent connection and egocentricity may be protective.

Original languageEnglish
Pages (from-to)553-561
Number of pages9
JournalJapanese journal of clinical oncology
Volume38
Issue number8
DOIs
Publication statusPublished - Sep 19 2008

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Histrionic Personality Disorder
Personality
Colorectal Neoplasms
Logistic Models
Altruism
Equipment and Supplies
Happiness
Frustration
Ethics
Case-Control Studies
Life Style
Neoplasms
Japan
Body Mass Index
Population

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

Cite this

Nagano, J., Kono, S., Toyomura, K., Mizoue, T., Yin, G., Mibu, R., ... Imaizumi, N. (2008). Personality and colorectal cancer: The Fukuoka Colorectal Cancer Study. Japanese journal of clinical oncology, 38(8), 553-561. https://doi.org/10.1093/jjco/hyn067

Personality and colorectal cancer : The Fukuoka Colorectal Cancer Study. / Nagano, Jun; Kono, Suminori; Toyomura, Kengo; Mizoue, Tetsuya; Yin, Guang; Mibu, Ryuichi; Tanaka, Masao; Kakeji, Yoshihiro; Maehara, Yoshihiko; Okamura, Takeshi; Ikejiri, Koji; Futami, Kitaroh; Yasunami, Yohichi; Maekawa, Takafumi; Takenaka, Kenji; Ichimiya, Hitoshi; Imaizumi, Nobutoshi.

In: Japanese journal of clinical oncology, Vol. 38, No. 8, 19.09.2008, p. 553-561.

Research output: Contribution to journalArticle

Nagano, J, Kono, S, Toyomura, K, Mizoue, T, Yin, G, Mibu, R, Tanaka, M, Kakeji, Y, Maehara, Y, Okamura, T, Ikejiri, K, Futami, K, Yasunami, Y, Maekawa, T, Takenaka, K, Ichimiya, H & Imaizumi, N 2008, 'Personality and colorectal cancer: The Fukuoka Colorectal Cancer Study', Japanese journal of clinical oncology, vol. 38, no. 8, pp. 553-561. https://doi.org/10.1093/jjco/hyn067
Nagano, Jun ; Kono, Suminori ; Toyomura, Kengo ; Mizoue, Tetsuya ; Yin, Guang ; Mibu, Ryuichi ; Tanaka, Masao ; Kakeji, Yoshihiro ; Maehara, Yoshihiko ; Okamura, Takeshi ; Ikejiri, Koji ; Futami, Kitaroh ; Yasunami, Yohichi ; Maekawa, Takafumi ; Takenaka, Kenji ; Ichimiya, Hitoshi ; Imaizumi, Nobutoshi. / Personality and colorectal cancer : The Fukuoka Colorectal Cancer Study. In: Japanese journal of clinical oncology. 2008 ; Vol. 38, No. 8. pp. 553-561.
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T2 - The Fukuoka Colorectal Cancer Study

AU - Nagano, Jun

AU - Kono, Suminori

AU - Toyomura, Kengo

AU - Mizoue, Tetsuya

AU - Yin, Guang

AU - Mibu, Ryuichi

AU - Tanaka, Masao

AU - Kakeji, Yoshihiro

AU - Maehara, Yoshihiko

AU - Okamura, Takeshi

AU - Ikejiri, Koji

AU - Futami, Kitaroh

AU - Yasunami, Yohichi

AU - Maekawa, Takafumi

AU - Takenaka, Kenji

AU - Ichimiya, Hitoshi

AU - Imaizumi, Nobutoshi

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N2 - Objective: Although personality factors, especially emotional suppression and loss-hopelessness, have been linked to the occurrence and progression of cancer, little is reported specifically on colorectal cancer. It has also been claimed that a "hysterical" personality characterized by exaggerated emotional expressions, egocentricity and ambivalent connection may be protective from cancer. This community-based case-control study examined whether personality factors relevant to emotional suppression or loss-hopelessness are associated with an increased risk of colorectal cancer, and whether factors related to the hysterical personality are associated with a decreased risk. Methods: The stress inventory (SI), a self-administered questionnaire to assess the possible disease-prone and other relevant personalities in Japanese, was completed by 497 patients with newly diagnosed colorectal cancer and 809 controls randomly selected in the Fukuoka area of Japan. Results: After controlling for age, sex and residence using a logistic regression model, none of the SI scales relevant to emotional suppression ("unfulfilled needs for acceptance", "altruism", "rationalizing conflicts/frustrations") or loss-hopelessness ("low sense of control", "object-dependence/loss", "object-dependence/ happiness") was related to colorectal cancer. On the other hand, two scales representing elements of the hysterical personality, "object-dependence/ambivalence" and "egoism" were protectively associated with risk. Additional adjustment for body-mass index and lifestyle factors did not materially change these associations. Conclusions: Although personalities relevant to the emotional suppression or loss-hopelessness may not be a risk factor for colorectal cancer in the Japanese population, ambivalent connection and egocentricity may be protective.

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