Pharmacological properties of quisqualate- and kainate-preferring glutamate receptors induced in Xenopus oocytes by rat and chick brain mRNA

H. Sugiyama, M. Watanabe, H. Taji, Y. Yamamoto, I. Ito

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Quisqualate- and kainate-preferring glutamate receptors were studied in Xenopus oocytes injected with rat and chick brain mRNA. All ligands effective at ionotropic quisqualate sites, agonists as well as antagonists, were found to inhibit kainate responses. Ionotropic quisqualate and kainate responses were distinguished by γ-l-glutamylglycine but not by its d-isomer. No difference was detected between responses induced by rat brain mRNA and chick brain mRNA, suggesting that the properties on non-N-methyl-d-aspartate-type glutamate receptors of rat and chick brains are essentially the same.

Original languageEnglish
Pages (from-to)164-167
Number of pages4
JournalNeuroscience Research
Volume7
Issue number2
DOIs
Publication statusPublished - Nov 1989

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Pharmacological properties of quisqualate- and kainate-preferring glutamate receptors induced in Xenopus oocytes by rat and chick brain mRNA'. Together they form a unique fingerprint.

Cite this