Pharmacological properties of quisqualate- and kainate-preferring glutamate receptors induced in Xenopus oocytes by rat and chick brain mRNA

H. Sugiyama, M. Watanabe, H. Taji, Y. Yamamoto, Isao Ito

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Quisqualate- and kainate-preferring glutamate receptors were studied in Xenopus oocytes injected with rat and chick brain mRNA. All ligands effective at ionotropic quisqualate sites, agonists as well as antagonists, were found to inhibit kainate responses. Ionotropic quisqualate and kainate responses were distinguished by γ-l-glutamylglycine but not by its d-isomer. No difference was detected between responses induced by rat brain mRNA and chick brain mRNA, suggesting that the properties on non-N-methyl-d-aspartate-type glutamate receptors of rat and chick brains are essentially the same.

Original languageEnglish
Pages (from-to)164-167
Number of pages4
JournalNeuroscience Research
Volume7
Issue number2
DOIs
Publication statusPublished - Jan 1 1989
Externally publishedYes

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Quisqualic Acid
Kainic Acid
Glutamate Receptors
Xenopus
Oocytes
Pharmacology
Messenger RNA
Brain
Ligands

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Pharmacological properties of quisqualate- and kainate-preferring glutamate receptors induced in Xenopus oocytes by rat and chick brain mRNA. / Sugiyama, H.; Watanabe, M.; Taji, H.; Yamamoto, Y.; Ito, Isao.

In: Neuroscience Research, Vol. 7, No. 2, 01.01.1989, p. 164-167.

Research output: Contribution to journalArticle

Sugiyama, H. ; Watanabe, M. ; Taji, H. ; Yamamoto, Y. ; Ito, Isao. / Pharmacological properties of quisqualate- and kainate-preferring glutamate receptors induced in Xenopus oocytes by rat and chick brain mRNA. In: Neuroscience Research. 1989 ; Vol. 7, No. 2. pp. 164-167.
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