Herein, we report on a new 19 F MRI probe for the detection and imaging of H 2 O 2 . Our designed 2-fluorophenylboronic acid-based 19 F probe promptly reacted with H 2 O 2 to produce 2-fluorophenol via boronic acid oxidation. The accompanying 19 F chemical-shift change reached 31 ppm under our experimental conditions. Such a large chemical-shift change allowed for the imaging of H 2 O 2 by 19 F chemical-shift-selective MRI.
All Science Journal Classification (ASJC) codes
- Analytical Chemistry