Phosphatidylserine-selective conformational change of α-helix peptide, Td3717, and its ability to transfect cancer cells

Shinichi Kuriyama, Kanako Nishimura, Yasushi Taguchi, Kazutoshi Yanagibashi, Yoshiki Katayama, Takuro Niidome

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)

    Abstract

    A synthetic peptide, Td3717, showed selective affinity for anionic phospholipids, phosphatidylserine and phosphatidylglycerol, and formed an amphiphilic α-helical structure. This specificity originated not only from electrostatic interactions, but also from the primary amino acid sequence and overall structure of the peptide.

    Original languageEnglish
    Pages (from-to)684-685
    Number of pages2
    JournalChemistry Letters
    Volume38
    Issue number7
    DOIs
    Publication statusPublished - Jul 20 2009

    All Science Journal Classification (ASJC) codes

    • Chemistry(all)

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