Photonavigation of cell migration on caged cell-culturing substrates

Jun Nakanishi, Tohru Takarada, Yukiko Kikuchi, Hidekazu Nakyama, Kazuo Yamaguchi, Mizuo Maeda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cell migration is a fundamental biological activity, which is involved in both physiological and pathological processes, including embryonic development, inflammation, cancer cell migration, and metastasis. In the present study, we have developed a new method for studying the migration of single cells using a "Caged Cell-Culturing Substrate", which we had recently developed. Cells attached onto a single cell array were released from their geometrical confinements by illumination, which switched on migration of the cells onto the illuminated regions. The formation of cell-adhesive regions can be conducted under fluorescence microscopes. The present method will be useful for studying the regulatory mechanism of cell motility.

Original languageEnglish
Title of host publication54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan
Pages2341
Number of pages1
Volume54
Edition1
Publication statusPublished - 2005
Externally publishedYes
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: May 25 2005May 27 2005

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period5/25/055/27/05

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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  • Cite this

    Nakanishi, J., Takarada, T., Kikuchi, Y., Nakyama, H., Yamaguchi, K., & Maeda, M. (2005). Photonavigation of cell migration on caged cell-culturing substrates. In 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan (1 ed., Vol. 54, pp. 2341)