Photothermal reshaping of gold nanorods prevents further cell death

Hironobu Takahashi, Takuro Niidome, Ayuko Nariai, Yasuro Niidome, Sunao Yamada

    Research output: Contribution to journalArticlepeer-review

    75 Citations (Scopus)

    Abstract

    The combined use of phosphatidylcholine passivated gold nanorods (PC-NRs) and pulsed near-infrared (near-IR) irradiation resulted in cell death. Pulsed near-IR laser irradiation also induced reshaping of PC-NRs into spherical nanoparticles. Since reshaped particles showed no absorption in the near-IR region, successive laser irradiation did not affect cells. Photo-reshaping of PC-NRs is expected to be advantageous in preventing unwanted cell damage following destruction of target cells.

    Original languageEnglish
    Article number024
    Pages (from-to)4431-4435
    Number of pages5
    JournalNanotechnology
    Volume17
    Issue number17
    DOIs
    Publication statusPublished - Aug 1 2006

    All Science Journal Classification (ASJC) codes

    • Bioengineering
    • Chemistry(all)
    • Materials Science(all)
    • Mechanics of Materials
    • Mechanical Engineering
    • Electrical and Electronic Engineering

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