Phyllodes tumor in adolescents. Report of two cases and review of the literature

Yosuke Adachi, Tetsuya Matsushima, Akinori Kido, Reishi Shimono, Eisuke Adachi, Akito Matsukuma, Masaki Mori, Keizo Sugimachi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Two cases of a phyllodes tumor in adolescents are herein reported. A 15-year-old girl complained of right breast enlargement and underwent a local excision. The tumor, measuring 11 cm in size, indicated a grossly cabbage-like appearance and an extremely hypercellular stroma with minimal atypia or mitosis. 13-year-old girl exhibited a painless large breast tumor and also underwent a local excision. The tumor, measuring 11 cm in size, was lobulated with cystic spaces and composed of fibroblastic stroma and benign ducts. A total of 291 cases of phyllodes tumors collected from the literature were then reviewed, comparing the 97 adolescent cases with the 194 adult cases. Phyllodes tumor in adolescents was characterized by local excision (96%), benign histology (91%), low incidence of recurrence (12%) and metastasis (3%), and high survival rate (97%). These cases indicate that phyllodes tumors in adolescents have a more benign course and a more favorable outcome than in adults, and a local excision is preferred to mastectomy as the initial therapy.

Original languageEnglish
Pages (from-to)285-293
Number of pages9
JournalBreast Disease
Volume6
Issue number4
Publication statusPublished - Oct 1 1993

Fingerprint

Phyllodes Tumor
Brassica
Mastectomy
Mitosis
Neoplasms
Histology
Breast
Survival Rate
Breast Neoplasms
Neoplasm Metastasis
Recurrence
Incidence

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Adachi, Y., Matsushima, T., Kido, A., Shimono, R., Adachi, E., Matsukuma, A., ... Sugimachi, K. (1993). Phyllodes tumor in adolescents. Report of two cases and review of the literature. Breast Disease, 6(4), 285-293.

Phyllodes tumor in adolescents. Report of two cases and review of the literature. / Adachi, Yosuke; Matsushima, Tetsuya; Kido, Akinori; Shimono, Reishi; Adachi, Eisuke; Matsukuma, Akito; Mori, Masaki; Sugimachi, Keizo.

In: Breast Disease, Vol. 6, No. 4, 01.10.1993, p. 285-293.

Research output: Contribution to journalArticle

Adachi, Y, Matsushima, T, Kido, A, Shimono, R, Adachi, E, Matsukuma, A, Mori, M & Sugimachi, K 1993, 'Phyllodes tumor in adolescents. Report of two cases and review of the literature', Breast Disease, vol. 6, no. 4, pp. 285-293.
Adachi Y, Matsushima T, Kido A, Shimono R, Adachi E, Matsukuma A et al. Phyllodes tumor in adolescents. Report of two cases and review of the literature. Breast Disease. 1993 Oct 1;6(4):285-293.
Adachi, Yosuke ; Matsushima, Tetsuya ; Kido, Akinori ; Shimono, Reishi ; Adachi, Eisuke ; Matsukuma, Akito ; Mori, Masaki ; Sugimachi, Keizo. / Phyllodes tumor in adolescents. Report of two cases and review of the literature. In: Breast Disease. 1993 ; Vol. 6, No. 4. pp. 285-293.
@article{c14b53ea999d442b9c555e3b56b83e8c,
title = "Phyllodes tumor in adolescents. Report of two cases and review of the literature",
abstract = "Two cases of a phyllodes tumor in adolescents are herein reported. A 15-year-old girl complained of right breast enlargement and underwent a local excision. The tumor, measuring 11 cm in size, indicated a grossly cabbage-like appearance and an extremely hypercellular stroma with minimal atypia or mitosis. 13-year-old girl exhibited a painless large breast tumor and also underwent a local excision. The tumor, measuring 11 cm in size, was lobulated with cystic spaces and composed of fibroblastic stroma and benign ducts. A total of 291 cases of phyllodes tumors collected from the literature were then reviewed, comparing the 97 adolescent cases with the 194 adult cases. Phyllodes tumor in adolescents was characterized by local excision (96{\%}), benign histology (91{\%}), low incidence of recurrence (12{\%}) and metastasis (3{\%}), and high survival rate (97{\%}). These cases indicate that phyllodes tumors in adolescents have a more benign course and a more favorable outcome than in adults, and a local excision is preferred to mastectomy as the initial therapy.",
author = "Yosuke Adachi and Tetsuya Matsushima and Akinori Kido and Reishi Shimono and Eisuke Adachi and Akito Matsukuma and Masaki Mori and Keizo Sugimachi",
year = "1993",
month = "10",
day = "1",
language = "English",
volume = "6",
pages = "285--293",
journal = "Breast Disease",
issn = "0888-6008",
publisher = "IOS Press",
number = "4",

}

TY - JOUR

T1 - Phyllodes tumor in adolescents. Report of two cases and review of the literature

AU - Adachi, Yosuke

AU - Matsushima, Tetsuya

AU - Kido, Akinori

AU - Shimono, Reishi

AU - Adachi, Eisuke

AU - Matsukuma, Akito

AU - Mori, Masaki

AU - Sugimachi, Keizo

PY - 1993/10/1

Y1 - 1993/10/1

N2 - Two cases of a phyllodes tumor in adolescents are herein reported. A 15-year-old girl complained of right breast enlargement and underwent a local excision. The tumor, measuring 11 cm in size, indicated a grossly cabbage-like appearance and an extremely hypercellular stroma with minimal atypia or mitosis. 13-year-old girl exhibited a painless large breast tumor and also underwent a local excision. The tumor, measuring 11 cm in size, was lobulated with cystic spaces and composed of fibroblastic stroma and benign ducts. A total of 291 cases of phyllodes tumors collected from the literature were then reviewed, comparing the 97 adolescent cases with the 194 adult cases. Phyllodes tumor in adolescents was characterized by local excision (96%), benign histology (91%), low incidence of recurrence (12%) and metastasis (3%), and high survival rate (97%). These cases indicate that phyllodes tumors in adolescents have a more benign course and a more favorable outcome than in adults, and a local excision is preferred to mastectomy as the initial therapy.

AB - Two cases of a phyllodes tumor in adolescents are herein reported. A 15-year-old girl complained of right breast enlargement and underwent a local excision. The tumor, measuring 11 cm in size, indicated a grossly cabbage-like appearance and an extremely hypercellular stroma with minimal atypia or mitosis. 13-year-old girl exhibited a painless large breast tumor and also underwent a local excision. The tumor, measuring 11 cm in size, was lobulated with cystic spaces and composed of fibroblastic stroma and benign ducts. A total of 291 cases of phyllodes tumors collected from the literature were then reviewed, comparing the 97 adolescent cases with the 194 adult cases. Phyllodes tumor in adolescents was characterized by local excision (96%), benign histology (91%), low incidence of recurrence (12%) and metastasis (3%), and high survival rate (97%). These cases indicate that phyllodes tumors in adolescents have a more benign course and a more favorable outcome than in adults, and a local excision is preferred to mastectomy as the initial therapy.

UR - http://www.scopus.com/inward/record.url?scp=0027504442&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027504442&partnerID=8YFLogxK

M3 - Article

VL - 6

SP - 285

EP - 293

JO - Breast Disease

JF - Breast Disease

SN - 0888-6008

IS - 4

ER -