Physical comorbidities in older adults receiving antidepressants in Asia

Xiao Mei Zhong, Min Dong, Fei Wang, Qinge Zhang, Gabor S. Ungvari, Chee H. Ng, Helen F.K. Chiu, Tian Mei Si, Kang Sim, Ajit Avasthi, Sandeep Grover, Mian Yoon Chong, Kok Yoon Chee, Shigenobu Kanba, Min Soo Lee, Shu Yu Yang, Pichet Udomratn, Roy A. Kallivayalil, Andi J. Tanra, Margarita M. Maramis & 6 others Winston W. Shen, Norman Sartorius, Rathi Mahendran, Chay Hoon Tan, Naotaka Shinfuku, Yu Tao Xiang

Research output: Contribution to journalArticle

Abstract

Background: The present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia. Methods: Demographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Standardized data collection procedure was used to record demographic and clinical data. Results: Proportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR = 1.7, P < 0.001), higher number of depressive symptoms (OR = 1.09, P = 0.016), being treated in psychiatric hospital (OR = 0.5, P = 0.002), living in high income countries/territories (OR = 2.4, P = 0.002), use of benzodiazepines (OR = 1.4, P = 0.013) and diagnosis of ‘other psychiatric disorders’ (except mood, anxiety disorders and schizophrenia) (OR = 2.7, P < 0.001) were significantly associated with physical comorbidities. Conclusions: Physical comorbidities in older patients prescribed with antidepressants were common in Asia. Integrating physical care into the treatment of older psychiatric patients should be urgently considered.

Original languageEnglish
Pages (from-to)351-356
Number of pages6
JournalPsychogeriatrics
Volume18
Issue number5
DOIs
Publication statusPublished - Sep 1 2018

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Antidepressive Agents
Comorbidity
Demography
Psychiatry
Psychiatric Hospitals
Anxiety Disorders
Mood Disorders
Benzodiazepines
Mental Disorders
Prescriptions
Schizophrenia
Logistic Models
Regression Analysis
Databases
Depression
Research
Therapeutics

All Science Journal Classification (ASJC) codes

  • Gerontology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

Cite this

Zhong, X. M., Dong, M., Wang, F., Zhang, Q., Ungvari, G. S., Ng, C. H., ... Xiang, Y. T. (2018). Physical comorbidities in older adults receiving antidepressants in Asia. Psychogeriatrics, 18(5), 351-356. https://doi.org/10.1111/psyg.12327

Physical comorbidities in older adults receiving antidepressants in Asia. / Zhong, Xiao Mei; Dong, Min; Wang, Fei; Zhang, Qinge; Ungvari, Gabor S.; Ng, Chee H.; Chiu, Helen F.K.; Si, Tian Mei; Sim, Kang; Avasthi, Ajit; Grover, Sandeep; Chong, Mian Yoon; Chee, Kok Yoon; Kanba, Shigenobu; Lee, Min Soo; Yang, Shu Yu; Udomratn, Pichet; Kallivayalil, Roy A.; Tanra, Andi J.; Maramis, Margarita M.; Shen, Winston W.; Sartorius, Norman; Mahendran, Rathi; Tan, Chay Hoon; Shinfuku, Naotaka; Xiang, Yu Tao.

In: Psychogeriatrics, Vol. 18, No. 5, 01.09.2018, p. 351-356.

Research output: Contribution to journalArticle

Zhong, XM, Dong, M, Wang, F, Zhang, Q, Ungvari, GS, Ng, CH, Chiu, HFK, Si, TM, Sim, K, Avasthi, A, Grover, S, Chong, MY, Chee, KY, Kanba, S, Lee, MS, Yang, SY, Udomratn, P, Kallivayalil, RA, Tanra, AJ, Maramis, MM, Shen, WW, Sartorius, N, Mahendran, R, Tan, CH, Shinfuku, N & Xiang, YT 2018, 'Physical comorbidities in older adults receiving antidepressants in Asia', Psychogeriatrics, vol. 18, no. 5, pp. 351-356. https://doi.org/10.1111/psyg.12327
Zhong XM, Dong M, Wang F, Zhang Q, Ungvari GS, Ng CH et al. Physical comorbidities in older adults receiving antidepressants in Asia. Psychogeriatrics. 2018 Sep 1;18(5):351-356. https://doi.org/10.1111/psyg.12327
Zhong, Xiao Mei ; Dong, Min ; Wang, Fei ; Zhang, Qinge ; Ungvari, Gabor S. ; Ng, Chee H. ; Chiu, Helen F.K. ; Si, Tian Mei ; Sim, Kang ; Avasthi, Ajit ; Grover, Sandeep ; Chong, Mian Yoon ; Chee, Kok Yoon ; Kanba, Shigenobu ; Lee, Min Soo ; Yang, Shu Yu ; Udomratn, Pichet ; Kallivayalil, Roy A. ; Tanra, Andi J. ; Maramis, Margarita M. ; Shen, Winston W. ; Sartorius, Norman ; Mahendran, Rathi ; Tan, Chay Hoon ; Shinfuku, Naotaka ; Xiang, Yu Tao. / Physical comorbidities in older adults receiving antidepressants in Asia. In: Psychogeriatrics. 2018 ; Vol. 18, No. 5. pp. 351-356.
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T1 - Physical comorbidities in older adults receiving antidepressants in Asia

AU - Zhong, Xiao Mei

AU - Dong, Min

AU - Wang, Fei

AU - Zhang, Qinge

AU - Ungvari, Gabor S.

AU - Ng, Chee H.

AU - Chiu, Helen F.K.

AU - Si, Tian Mei

AU - Sim, Kang

AU - Avasthi, Ajit

AU - Grover, Sandeep

AU - Chong, Mian Yoon

AU - Chee, Kok Yoon

AU - Kanba, Shigenobu

AU - Lee, Min Soo

AU - Yang, Shu Yu

AU - Udomratn, Pichet

AU - Kallivayalil, Roy A.

AU - Tanra, Andi J.

AU - Maramis, Margarita M.

AU - Shen, Winston W.

AU - Sartorius, Norman

AU - Mahendran, Rathi

AU - Tan, Chay Hoon

AU - Shinfuku, Naotaka

AU - Xiang, Yu Tao

PY - 2018/9/1

Y1 - 2018/9/1

N2 - Background: The present study explored the patterns of physical comorbidities and their associated demographic and clinical factors in older psychiatric patients prescribed with antidepressants in Asia. Methods: Demographic and clinical information of 955 older adults were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Standardized data collection procedure was used to record demographic and clinical data. Results: Proportion of physical comorbidities in this cohort was 44%. Multiple logistic regression analyses showed that older age (OR = 1.7, P < 0.001), higher number of depressive symptoms (OR = 1.09, P = 0.016), being treated in psychiatric hospital (OR = 0.5, P = 0.002), living in high income countries/territories (OR = 2.4, P = 0.002), use of benzodiazepines (OR = 1.4, P = 0.013) and diagnosis of ‘other psychiatric disorders’ (except mood, anxiety disorders and schizophrenia) (OR = 2.7, P < 0.001) were significantly associated with physical comorbidities. Conclusions: Physical comorbidities in older patients prescribed with antidepressants were common in Asia. Integrating physical care into the treatment of older psychiatric patients should be urgently considered.

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