Phytochemistry of weigela x “kosteriana variegata” (Caprifoliaceae)

Nampoina Andriamisaina, Anne Claire Mitaine-Offer, Benoist Pruvot, Johanna Chluba, Tomofumi Miyamoto, Chiaki Tanaka, Marie Aleth Lacaille-Dubois

Research output: Contribution to journalArticle

2 Citations (Scopus)


One new triterpene glycoside 3-O-D-xylopyranosyl-(1→4)-[-D-glucopyranosyl-(1→3)]-D-xylopyranosyl-(1→4)-D-xylopyranosyl-(1→3)-L-rhamnopyranosyl-(1→2)-L-arabinopyranosyloleanolic acid, was isolated from Weigela x “kosteriana variegata” (Caprifoliaceae), with three known ones. Their structures were characterized by a combination of mass spectrometry and 1D and 2D NMR spectrocopic techniques including 1H- and 13C NMR, COSY, TOCSY, NOESY, HSQC, and HMBC experiments. The toxicological properties of some glycosides were determined with a zebrafish-based assay. The results show that the most active compounds were toxic to the larvae in the range of 1 M.

Original languageEnglish
Pages (from-to)403-406
Number of pages4
JournalNatural product communications
Issue number4
Publication statusPublished - Jan 1 2018


All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

Cite this

Andriamisaina, N., Mitaine-Offer, A. C., Pruvot, B., Chluba, J., Miyamoto, T., Tanaka, C., & Lacaille-Dubois, M. A. (2018). Phytochemistry of weigela x “kosteriana variegata” (Caprifoliaceae). Natural product communications, 13(4), 403-406.