Pneumonia and empyema caused by Streptococcus intermedius that shows the diagnostic importance of evaluating the microbiota in the lower respiratory tract

Shingo Noguchi, Kazuhiro Yatera, Toshinori Kawanami, Kei Yamasaki, Kazumasa Fukuda, Keisuke Naito, Kentarou Akata, Shuya Nagata, Hiroshi Ishimoto, Hatsumi Taniguchi, Hiroshi Mukae

Research output: Contribution to journalArticle

10 Citations (Scopus)


The bacterial species in the Streptococcus anginosus group (S. constellatus, S. anginosus, S. intermedius) are important causative pathogens of bacterial pneumonia, pulmonary abscesses and empyema. However, the bacteria in this group are primarily oral resident bacteria and unable to grow significantly on ordinary aerobic culture media. We experienced a case of pneumonia and empyema caused by Streptococcus intermedius detected using a 16S rRNA gene sequencing analysis of bronchoalveolar lavage fluid and pleural effusion, but not sputum. Even when applying the molecular method, sputum samples are occasionally unsuitable for identifying the causative pathogens of lower respiratory tract infections.

Original languageEnglish
Pages (from-to)47-50
Number of pages4
JournalInternal Medicine
Issue number1
Publication statusPublished - Jan 1 2014
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this