Polarity fluctuation inhibition by memory in collective cell motion

Katsuyoshi Matsushita, Shunsuke Yabunaka, Koichi Fujimoto

Research output: Contribution to journalArticlepeer-review

Abstract

Polarity memory often commonly stabilizes a polarity order in eukaryotic cells and self-propelled disks. This seemingly does not hold for dense cases: the polarity memory of dense cells stabilizes the order whereas that of dense self-propelled disks destabilizes their order. As the origin of this difference in the stabilization of the order from the aspect of eukaryotic cells, we consider the inhibition of polarity fluctuation, owing to polarity memory in dense cells. We examine this inhibition in model cells and evaluate the polarity fluctuation defined as the variance from the polarity order. We show that the polarity fluctuation is inhibited by the polarity memory averaging out configuration fluctuation. Therefore, the order is stabilized only against cell configuration fluctuation, but probably not against the internal polarity fluctuation considered in self-propelled disks. This result implies that the difference in the polarity order reflects the difference in fluctuations between these systems.

Original languageEnglish
Article number054801
Journaljournal of the physical society of japan
Volume90
Issue number5
DOIs
Publication statusPublished - May 15 2021

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

Fingerprint

Dive into the research topics of 'Polarity fluctuation inhibition by memory in collective cell motion'. Together they form a unique fingerprint.

Cite this