Polyacrylamide backbones for polyvalent bioconjugates using "post-click" chemistry

M. Nagao, Y. Kurebayashi, H. Seto, T. Takahashi, T. Suzuki, Yu Hoshino, Yoshiko Miura

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

This paper reports the synthesis and application of acrylamide-type neoglycoconjugates interacting with practical targets. Polymer backbones with acrylamide and acrylamide derivatives bearing alkyne groups were prepared using living radical polymerization. Oligosaccharides were introduced into the backbones using copper-catalysed azide-alkyne cycloaddition "post-click" chemistry.

Original languageEnglish
Pages (from-to)5920-5924
Number of pages5
JournalPolymer Chemistry
Volume7
Issue number38
DOIs
Publication statusPublished - Oct 14 2016

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Bearings (structural)
Click Chemistry
Oligosaccharides
Living polymerization
Cycloaddition
Acrylamide
Free radical polymerization
Polyacrylates
Alkynes
Derivatives
Copper
Polymers
Azides
Cycloaddition Reaction
Polymerization
polyacrylamide

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biochemistry
  • Polymers and Plastics
  • Organic Chemistry

Cite this

Polyacrylamide backbones for polyvalent bioconjugates using "post-click" chemistry. / Nagao, M.; Kurebayashi, Y.; Seto, H.; Takahashi, T.; Suzuki, T.; Hoshino, Yu; Miura, Yoshiko.

In: Polymer Chemistry, Vol. 7, No. 38, 14.10.2016, p. 5920-5924.

Research output: Contribution to journalArticle

Nagao, M. ; Kurebayashi, Y. ; Seto, H. ; Takahashi, T. ; Suzuki, T. ; Hoshino, Yu ; Miura, Yoshiko. / Polyacrylamide backbones for polyvalent bioconjugates using "post-click" chemistry. In: Polymer Chemistry. 2016 ; Vol. 7, No. 38. pp. 5920-5924.
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