Polymerization of diacetylene in casting parallel and anti-parallel β-sheet

Shiro Yasutake, Takeshi Mori, Keiji Minagawa, Masami Tanaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In the β sheet structure of the peptide, the distance among the β-strands are 5 Å. This distance corresponds with distance among the monomer units of diacetylene and diene. Therefore the β-sheet will be able to be cross-linked by introducing these monomer units into the diacetylene and diene into peptide that formed β-sheet by using this. In this work, we synthesized peptide 1-4. Peptide 1 and 2 were design to form anti-parallel β-sheet alone. On the other hand, peptide 3 and 4 were design to form parallel β-sheet by mixing them. Polymerization of 1 and 2 was conducted by UV irradiation. After the polymerization, UV-vis spectra of 1 and 2 in dichloroacetic acid had an absorbance at 573 nm that originates in poly diacetylene. The result of FT-IR measurement of them showed disappearance of a peak at 2250 cm-1 that originates in diacetylene. Amide I region suggested that the peptides formed anti-parallel β-sheet and random coil. Therefore, it seemed that polymerization occurred in the β-sheet formed part.

Original languageEnglish
Title of host publication54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan
Pages198
Number of pages1
Volume54
Edition1
Publication statusPublished - 2005
Externally publishedYes
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: May 25 2005May 27 2005

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period5/25/055/27/05

Fingerprint

Peptides
Casting
Polymerization
Monomers
Dichloroacetic acid
Amides
Irradiation

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Yasutake, S., Mori, T., Minagawa, K., & Tanaka, M. (2005). Polymerization of diacetylene in casting parallel and anti-parallel β-sheet. In 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan (1 ed., Vol. 54, pp. 198)

Polymerization of diacetylene in casting parallel and anti-parallel β-sheet. / Yasutake, Shiro; Mori, Takeshi; Minagawa, Keiji; Tanaka, Masami.

54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. Vol. 54 1. ed. 2005. p. 198.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yasutake, S, Mori, T, Minagawa, K & Tanaka, M 2005, Polymerization of diacetylene in casting parallel and anti-parallel β-sheet. in 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. 1 edn, vol. 54, pp. 198, 54th SPSJ Annual Meeting 2005, Yokohama, Japan, 5/25/05.
Yasutake S, Mori T, Minagawa K, Tanaka M. Polymerization of diacetylene in casting parallel and anti-parallel β-sheet. In 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. 1 ed. Vol. 54. 2005. p. 198
Yasutake, Shiro ; Mori, Takeshi ; Minagawa, Keiji ; Tanaka, Masami. / Polymerization of diacetylene in casting parallel and anti-parallel β-sheet. 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. Vol. 54 1. ed. 2005. pp. 198
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