Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

H. Nakashima, M. Akahoshi, Y. Tanaka, K. Yamaoka, E. Ogami, S. Nagano, Y. Arinobu, H. Niiro, T. Otsuka, Y. Niho

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Objective. To assess the association between polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Japanese people. Method. We examined the IL-10 receptor genotype of 109 SLE patients and 102 healthy subjects by the reverse transcription-polymerase chain reaction-restriction fragment length polymorphism (RT-PCR-RFLP) method. Results. There was no difference in the IL10R genotype frequencies of these two groups. Conclusion. The IL10R genotype does not determine susceptibility to SLE in Japanese people.

Original languageEnglish
Pages (from-to)1142-1144
Number of pages3
Issue number11
Publication statusPublished - Nov 1999


All Science Journal Classification (ASJC) codes

  • Rheumatology
  • Pharmacology (medical)

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