Polynucleotide can stabilize nucleobase-appended cholesterol gels

Munenori Numata; Seiji Shinkai

doi:10.1246/cl.2003.308

Polynucleotide can stabilize nucleobase-appended cholesterol gels

Munenori Numata, Seiji Shinkai

Institute for Advanced Study

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

The influence of added poly(A) or poly(C) on the gelation ability of uracil-appended cholesterol gelator was investigated. It was found that RNA-gelator complexes were formed in n-butanol solution. In particular, complementary poly(A) not only stabilized the gel system but also created the helical structure in the original gel phase.

Original language	English
Pages (from-to)	308-309
Number of pages	2
Journal	Chemistry Letters
Volume	32
Issue number	3
DOIs	https://doi.org/10.1246/cl.2003.308
Publication status	Published - Mar 5 2003

All Science Journal Classification (ASJC) codes

Chemistry(all)

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10.1246/cl.2003.308

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title = "Polynucleotide can stabilize nucleobase-appended cholesterol gels",

abstract = "The influence of added poly(A) or poly(C) on the gelation ability of uracil-appended cholesterol gelator was investigated. It was found that RNA-gelator complexes were formed in n-butanol solution. In particular, complementary poly(A) not only stabilized the gel system but also created the helical structure in the original gel phase.",

author = "Munenori Numata and Seiji Shinkai",

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AB - The influence of added poly(A) or poly(C) on the gelation ability of uracil-appended cholesterol gelator was investigated. It was found that RNA-gelator complexes were formed in n-butanol solution. In particular, complementary poly(A) not only stabilized the gel system but also created the helical structure in the original gel phase.

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Polynucleotide can stabilize nucleobase-appended cholesterol gels

Abstract

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