Abstract
Polymer complexes formed by schizophyllan and poly(C) showed a unique antihydrolysis effect when poly(C) was subjected to hydrolysis under basic conditions. The complexation reduced the hydrolysis rate to 80% of the control (i.e., poly(C) itself). However, when we added oligoamines with the intention of catalyzing the hydrolysis, the oligoamines induced dissociation of the complex instead of acceleration of the hydrolysis.
| Original language | English |
|---|---|
| Pages (from-to) | 178-185 |
| Number of pages | 8 |
| Journal | Bioorganic Chemistry |
| Volume | 29 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Jan 1 2001 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Biology
- Drug Discovery
- Organic Chemistry
Cite this
Polysaccharide-polynucleotide complexes (IV) : Antihydrolysis effect of the schizophyllan/poly(C) complex and the complex dissociation induced by amines. / Koumoto, Kazuya; Kimura, Taro; Sakurai, Kazuo; Shinkai, Seiji.
In: Bioorganic Chemistry, Vol. 29, No. 3, 01.01.2001, p. 178-185.Research output: Contribution to journal › Editorial
}
TY - JOUR
T1 - Polysaccharide-polynucleotide complexes (IV)
T2 - Antihydrolysis effect of the schizophyllan/poly(C) complex and the complex dissociation induced by amines
AU - Koumoto, Kazuya
AU - Kimura, Taro
AU - Sakurai, Kazuo
AU - Shinkai, Seiji
PY - 2001/1/1
Y1 - 2001/1/1
N2 - Polymer complexes formed by schizophyllan and poly(C) showed a unique antihydrolysis effect when poly(C) was subjected to hydrolysis under basic conditions. The complexation reduced the hydrolysis rate to 80% of the control (i.e., poly(C) itself). However, when we added oligoamines with the intention of catalyzing the hydrolysis, the oligoamines induced dissociation of the complex instead of acceleration of the hydrolysis.
AB - Polymer complexes formed by schizophyllan and poly(C) showed a unique antihydrolysis effect when poly(C) was subjected to hydrolysis under basic conditions. The complexation reduced the hydrolysis rate to 80% of the control (i.e., poly(C) itself). However, when we added oligoamines with the intention of catalyzing the hydrolysis, the oligoamines induced dissociation of the complex instead of acceleration of the hydrolysis.
UR - http://www.scopus.com/inward/record.url?scp=0035574756&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035574756&partnerID=8YFLogxK
U2 - 10.1006/bioo.2001.1202
DO - 10.1006/bioo.2001.1202
M3 - Editorial
C2 - 11437393
AN - SCOPUS:0035574756
VL - 29
SP - 178
EP - 185
JO - Bioorganic Chemistry
JF - Bioorganic Chemistry
SN - 0045-2068
IS - 3
ER -