Polysaccharide-Polynucleotide Complexes Part 17. Solvent Effects on Conformational-Transition of Polydeoxyadenylic Acid in the Complexes with Schizophyllan

Masami Mizu, Kazuya Koumoto, Taro Kimura, Kazuo Sakurai, Seiji Shinkai

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This paper examines the relationship between the conformation and solvent for the poly(Da)/s-SPG complex using circular dichroism in the 240-300 nm wavelength region. At the low temperature and low salt concentration, poly(Da) in the complex is estimated to take C2′-endo with a different torsional angle from the anti form. With increasing temperature, the circular dichroism (CD) spectrum starts to bear characteristics of C3′-endo and anti as a minority among the majority of C2′-endo and anti. When the salt concentration is increased, the spectrum becomes almost identical to that of the high temperature form under the non-salt condition. Therefore, addition of salt provides the identical effect to increasing temperature. D2O induces the same effect as decreasing temperature.

Original languageEnglish
Pages (from-to)714-720
Number of pages7
JournalPolymer Journal
Volume35
Issue number9
DOIs
Publication statusPublished - Nov 13 2003

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Sizofiran
Polynucleotides
Polysaccharides
Acids
Salts
Dichroism
Temperature
Conformations
poly(dA)
Wavelength

All Science Journal Classification (ASJC) codes

  • Polymers and Plastics
  • Materials Chemistry

Cite this

Polysaccharide-Polynucleotide Complexes Part 17. Solvent Effects on Conformational-Transition of Polydeoxyadenylic Acid in the Complexes with Schizophyllan. / Mizu, Masami; Koumoto, Kazuya; Kimura, Taro; Sakurai, Kazuo; Shinkai, Seiji.

In: Polymer Journal, Vol. 35, No. 9, 13.11.2003, p. 714-720.

Research output: Contribution to journalArticle

Mizu, Masami ; Koumoto, Kazuya ; Kimura, Taro ; Sakurai, Kazuo ; Shinkai, Seiji. / Polysaccharide-Polynucleotide Complexes Part 17. Solvent Effects on Conformational-Transition of Polydeoxyadenylic Acid in the Complexes with Schizophyllan. In: Polymer Journal. 2003 ; Vol. 35, No. 9. pp. 714-720.
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