Polysaccharide-polynucleotide interaction (XI); novel separation system of RNAs by using schizophyllan-appended column

Taro Kimura, Kazuya Koumoto, Masami Mizu, Kazuo Sakurai, Seiji Shinkai

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Schizophyllan belongs to the β-1,3-glucan family and can form a complex with particular polynucleotides.1 We applied this complexation to specifically separate polynucleotides by constructing a schizophyllan-appended column. The column trapped poly(C) and poly(A), while it did not show any affinity to poly(G), which is consistent with the experimental results obtained in the homogenous solution. The present results indicate that the s-SPG column can be a new separation device for biomolecules.

Original languageEnglish
Pages (from-to)1240-1241
Number of pages2
JournalChemistry Letters
Issue number12
DOIs
Publication statusPublished - Dec 5 2002

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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