Poorly versus moderately differentiated hepatocellular carcinoma: Vascularity assessment by computed tomographic hepatic angiography in correlation with histologically counted number of unpaired arteries

Yoshiki Asayama, Kengo Yoshimitsu, Hiroyuki Irie, Yunosuke Nishihara, Shinichi Aishima, Tsuyoshi Tajima, Masakazu Hirakawa, Kousei Ishigami, Daisuke Kakihara, Akinobu Taketomi, Hiroshi Honda

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Abstract

PURPOSE: To determine the vascularity of moderately and poorly differentiated hepatocellular carcinoma (mHCC and pHCC, respectively) as observed on and depicted by computed tomography during hepatic angiography and to perform pathological correlation. MATERIALS AND METHODS: Eighty-seven consecutive patients with 89 hepatocellular carcinomas (61 mHCCs and 28 pHCCs) were surgically resected in our hospital. The degree of contrast enhancement on computed tomography during hepatic angiography of the tumors was classified into high attenuation (H), isoattenuation (I), and low attenuation (L). We also examined hepatocellular carcinomas measuring less than 4 cm in diameter. Pathologically, the number of unpaired arteries in the tumors was determined (×200 magnification). RESULTS: The number of mHCC and pHCC in each degree of enhancement (H/I/L) was 59:1:1 and 19:6:3, respectively. The number of mHCC and pHCC measuring less than 4 cm without portal invasion was 48 and 15, respectively; the number of these tumors in each degree of enhancement (H/I/L) was 47:1:0 and 11:3:1, respectively. The mean number of unpaired arteries was 8.9 ± 4.4 in mHCC and 5.2 ± 4.3 in pHCC, respectively. All results were statistically significant (P < 0.01). CONCLUSIONS: Our results indicated that the arterial blood supply of pHCC was lower than that of mHCC.

Original languageEnglish
Pages (from-to)188-192
Number of pages5
JournalJournal of Computer Assisted Tomography
Volume31
Issue number2
DOIs
Publication statusPublished - Mar 1 2007

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Hepatocellular Carcinoma
Angiography
Arteries
Liver
Tomography
Neoplasms

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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Poorly versus moderately differentiated hepatocellular carcinoma : Vascularity assessment by computed tomographic hepatic angiography in correlation with histologically counted number of unpaired arteries. / Asayama, Yoshiki; Yoshimitsu, Kengo; Irie, Hiroyuki; Nishihara, Yunosuke; Aishima, Shinichi; Tajima, Tsuyoshi; Hirakawa, Masakazu; Ishigami, Kousei; Kakihara, Daisuke; Taketomi, Akinobu; Honda, Hiroshi.

In: Journal of Computer Assisted Tomography, Vol. 31, No. 2, 01.03.2007, p. 188-192.

Research output: Contribution to journalArticle

Asayama, Yoshiki ; Yoshimitsu, Kengo ; Irie, Hiroyuki ; Nishihara, Yunosuke ; Aishima, Shinichi ; Tajima, Tsuyoshi ; Hirakawa, Masakazu ; Ishigami, Kousei ; Kakihara, Daisuke ; Taketomi, Akinobu ; Honda, Hiroshi. / Poorly versus moderately differentiated hepatocellular carcinoma : Vascularity assessment by computed tomographic hepatic angiography in correlation with histologically counted number of unpaired arteries. In: Journal of Computer Assisted Tomography. 2007 ; Vol. 31, No. 2. pp. 188-192.
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abstract = "PURPOSE: To determine the vascularity of moderately and poorly differentiated hepatocellular carcinoma (mHCC and pHCC, respectively) as observed on and depicted by computed tomography during hepatic angiography and to perform pathological correlation. MATERIALS AND METHODS: Eighty-seven consecutive patients with 89 hepatocellular carcinomas (61 mHCCs and 28 pHCCs) were surgically resected in our hospital. The degree of contrast enhancement on computed tomography during hepatic angiography of the tumors was classified into high attenuation (H), isoattenuation (I), and low attenuation (L). We also examined hepatocellular carcinomas measuring less than 4 cm in diameter. Pathologically, the number of unpaired arteries in the tumors was determined (×200 magnification). RESULTS: The number of mHCC and pHCC in each degree of enhancement (H/I/L) was 59:1:1 and 19:6:3, respectively. The number of mHCC and pHCC measuring less than 4 cm without portal invasion was 48 and 15, respectively; the number of these tumors in each degree of enhancement (H/I/L) was 47:1:0 and 11:3:1, respectively. The mean number of unpaired arteries was 8.9 ± 4.4 in mHCC and 5.2 ± 4.3 in pHCC, respectively. All results were statistically significant (P < 0.01). CONCLUSIONS: Our results indicated that the arterial blood supply of pHCC was lower than that of mHCC.",
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T2 - Vascularity assessment by computed tomographic hepatic angiography in correlation with histologically counted number of unpaired arteries

AU - Asayama, Yoshiki

AU - Yoshimitsu, Kengo

AU - Irie, Hiroyuki

AU - Nishihara, Yunosuke

AU - Aishima, Shinichi

AU - Tajima, Tsuyoshi

AU - Hirakawa, Masakazu

AU - Ishigami, Kousei

AU - Kakihara, Daisuke

AU - Taketomi, Akinobu

AU - Honda, Hiroshi

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N2 - PURPOSE: To determine the vascularity of moderately and poorly differentiated hepatocellular carcinoma (mHCC and pHCC, respectively) as observed on and depicted by computed tomography during hepatic angiography and to perform pathological correlation. MATERIALS AND METHODS: Eighty-seven consecutive patients with 89 hepatocellular carcinomas (61 mHCCs and 28 pHCCs) were surgically resected in our hospital. The degree of contrast enhancement on computed tomography during hepatic angiography of the tumors was classified into high attenuation (H), isoattenuation (I), and low attenuation (L). We also examined hepatocellular carcinomas measuring less than 4 cm in diameter. Pathologically, the number of unpaired arteries in the tumors was determined (×200 magnification). RESULTS: The number of mHCC and pHCC in each degree of enhancement (H/I/L) was 59:1:1 and 19:6:3, respectively. The number of mHCC and pHCC measuring less than 4 cm without portal invasion was 48 and 15, respectively; the number of these tumors in each degree of enhancement (H/I/L) was 47:1:0 and 11:3:1, respectively. The mean number of unpaired arteries was 8.9 ± 4.4 in mHCC and 5.2 ± 4.3 in pHCC, respectively. All results were statistically significant (P < 0.01). CONCLUSIONS: Our results indicated that the arterial blood supply of pHCC was lower than that of mHCC.

AB - PURPOSE: To determine the vascularity of moderately and poorly differentiated hepatocellular carcinoma (mHCC and pHCC, respectively) as observed on and depicted by computed tomography during hepatic angiography and to perform pathological correlation. MATERIALS AND METHODS: Eighty-seven consecutive patients with 89 hepatocellular carcinomas (61 mHCCs and 28 pHCCs) were surgically resected in our hospital. The degree of contrast enhancement on computed tomography during hepatic angiography of the tumors was classified into high attenuation (H), isoattenuation (I), and low attenuation (L). We also examined hepatocellular carcinomas measuring less than 4 cm in diameter. Pathologically, the number of unpaired arteries in the tumors was determined (×200 magnification). RESULTS: The number of mHCC and pHCC in each degree of enhancement (H/I/L) was 59:1:1 and 19:6:3, respectively. The number of mHCC and pHCC measuring less than 4 cm without portal invasion was 48 and 15, respectively; the number of these tumors in each degree of enhancement (H/I/L) was 47:1:0 and 11:3:1, respectively. The mean number of unpaired arteries was 8.9 ± 4.4 in mHCC and 5.2 ± 4.3 in pHCC, respectively. All results were statistically significant (P < 0.01). CONCLUSIONS: Our results indicated that the arterial blood supply of pHCC was lower than that of mHCC.

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