Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly

Haruka Sakaue, Takuya Shiota, Naoya Ishizaka, Shin Kawano, Yasushi Tamura, Kher Shing Tan, Kenichiro Imai, Chie Motono, Takatsugu Hirokawa, Kentaro Taki, Non Miyata, Osamu Kuge, Trevor Lithgow, Toshiya Endo

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The mitochondrial protein entry gate, the TOM complex, undergoes a dynamic conversion between the fully assembled trimer and the dimer lacking Tom22. Mitochondrial porin, Por1, regulates the trimer assembly by chaperoning newly imported Tom22 and dimer-trimer dependent functions of the TOM complex together with Tom6.

Original languageEnglish
Pages (from-to)1044-1055.e8
JournalMolecular Cell
Volume73
Issue number5
DOIs
Publication statusPublished - Mar 7 2019

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Porins
Mitochondrial Proteins
TOM translocase

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology

Cite this

Sakaue, H., Shiota, T., Ishizaka, N., Kawano, S., Tamura, Y., Tan, K. S., ... Endo, T. (2019). Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly. Molecular Cell, 73(5), 1044-1055.e8. https://doi.org/10.1016/j.molcel.2019.01.003

Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly. / Sakaue, Haruka; Shiota, Takuya; Ishizaka, Naoya; Kawano, Shin; Tamura, Yasushi; Tan, Kher Shing; Imai, Kenichiro; Motono, Chie; Hirokawa, Takatsugu; Taki, Kentaro; Miyata, Non; Kuge, Osamu; Lithgow, Trevor; Endo, Toshiya.

In: Molecular Cell, Vol. 73, No. 5, 07.03.2019, p. 1044-1055.e8.

Research output: Contribution to journalArticle

Sakaue, H, Shiota, T, Ishizaka, N, Kawano, S, Tamura, Y, Tan, KS, Imai, K, Motono, C, Hirokawa, T, Taki, K, Miyata, N, Kuge, O, Lithgow, T & Endo, T 2019, 'Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly', Molecular Cell, vol. 73, no. 5, pp. 1044-1055.e8. https://doi.org/10.1016/j.molcel.2019.01.003
Sakaue H, Shiota T, Ishizaka N, Kawano S, Tamura Y, Tan KS et al. Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly. Molecular Cell. 2019 Mar 7;73(5):1044-1055.e8. https://doi.org/10.1016/j.molcel.2019.01.003
Sakaue, Haruka ; Shiota, Takuya ; Ishizaka, Naoya ; Kawano, Shin ; Tamura, Yasushi ; Tan, Kher Shing ; Imai, Kenichiro ; Motono, Chie ; Hirokawa, Takatsugu ; Taki, Kentaro ; Miyata, Non ; Kuge, Osamu ; Lithgow, Trevor ; Endo, Toshiya. / Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly. In: Molecular Cell. 2019 ; Vol. 73, No. 5. pp. 1044-1055.e8.
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