@article{2fb1449be0b8407e868aaf6265f8d4c4,
title = "Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly",
abstract = "The mitochondrial protein entry gate, the TOM complex, undergoes a dynamic conversion between the fully assembled trimer and the dimer lacking Tom22. Mitochondrial porin, Por1, regulates the trimer assembly by chaperoning newly imported Tom22 and dimer-trimer dependent functions of the TOM complex together with Tom6.",
author = "Haruka Sakaue and Takuya Shiota and Naoya Ishizaka and Shin Kawano and Yasushi Tamura and Tan, {Kher Shing} and Kenichiro Imai and Chie Motono and Takatsugu Hirokawa and Kentaro Taki and Non Miyata and Osamu Kuge and Trevor Lithgow and Toshiya Endo",
note = "Funding Information: We thank the members of the Endo lab for discussions and critical comments on the manuscript. We also thank Drs. K. Yunoki and C. Saito for technical assistance. This work was supported by JSPS KAKENHI to Y.T. ( 15H05595 and 17H06414 ) and T.E. ( 15H05705 and 2222703 ), by a JST CREST ( JPMJCR12M1 ), an AMED-Prime ( JP18gm5910026 ), and a grant from the Takeda Science Foundation to T.E, and by grants from the Australian Research Council to T.L. ( FL30100038 and DP160100227 ). The following grants are also acknowledged: Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research [BINDS]) from AMED ( JP18am0101114 ) to C.M., K.I., and T.H.; and JSPS KAKENHI ( 16K21680 and 18K11543 ) to K.I. We are grateful to K. Kaibuchi and T. Nishioka (Nagoya University Graduate School of Medicine) for MS analyses. Funding Information: We thank the members of the Endo lab for discussions and critical comments on the manuscript. We also thank Drs. K. Yunoki and C. Saito for technical assistance. This work was supported by JSPS KAKENHI to Y.T. (15H05595 and 17H06414) and T.E. (15H05705 and 2222703), by a JST CREST (JPMJCR12M1), an AMED-Prime (JP18gm5910026), and a grant from the Takeda Science Foundation to T.E, and by grants from the Australian Research Council to T.L. (FL30100038 and DP160100227). The following grants are also acknowledged: Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research [BINDS]) from AMED (JP18am0101114) to C.M., K.I., and T.H.; and JSPS KAKENHI (16K21680 and 18K11543) to K.I. We are grateful to K. Kaibuchi and T. Nishioka (Nagoya University Graduate School of Medicine) for MS analyses. Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",
year = "2019",
month = mar,
day = "7",
doi = "10.1016/j.molcel.2019.01.003",
language = "English",
volume = "73",
pages = "1044--1055.e8",
journal = "Molecular Cell",
issn = "1097-2765",
publisher = "Cell Press",
number = "5",
}