Positron-emission tomography in stroke associated with antiphospholipid syndrome

Tetsuro Sayama; T. Inamura; T. Morioka; S. Inoha; A. Nakamizo; K. Ikezaki; T. Matsushima; M. Sasaki; M. Fukui

doi:10.1053/radi.2001.0329

Positron-emission tomography in stroke associated with antiphospholipid syndrome

Tetsuro Sayama, T. Inamura, T. Morioka, S. Inoha, A. Nakamizo, K. Ikezaki, T. Matsushima, M. Sasaki, M. Fukui

Research output: Contribution to journal › Article › peer-review

Abstract

Angiography in a 35-year-old man, with a history of transient ischaemic attacks and a convulsive seizure, showed bilateral stenosis of the distal internal carotid arteries, and positron-emission tomography (PET) revealed inadequate blood flow in the right frontal lobe (decreased blood flow, increased oxygen extraction). A lupus anticoagulant and an elevated anticardiolipin antibody concentration were detected in serum. The patient's condition progressed from ischaemia to infarction resulting in the diagnosis of antiphospholipid syndrome and steroid and antiplatelet treatment resulted in an improved neurologic state and laboratory findings. PET showed better correlation with clinical features than carotid angiography in this case of antiphospholipid syndrome leading to stroke.

Original language	English
Pages (from-to)	209-214
Number of pages	6
Journal	Radiography
Volume	7
Issue number	3
DOIs	https://doi.org/10.1053/radi.2001.0329
Publication status	Published - 2001

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

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10.1053/radi.2001.0329

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title = "Positron-emission tomography in stroke associated with antiphospholipid syndrome",

abstract = "Angiography in a 35-year-old man, with a history of transient ischaemic attacks and a convulsive seizure, showed bilateral stenosis of the distal internal carotid arteries, and positron-emission tomography (PET) revealed inadequate blood flow in the right frontal lobe (decreased blood flow, increased oxygen extraction). A lupus anticoagulant and an elevated anticardiolipin antibody concentration were detected in serum. The patient's condition progressed from ischaemia to infarction resulting in the diagnosis of antiphospholipid syndrome and steroid and antiplatelet treatment resulted in an improved neurologic state and laboratory findings. PET showed better correlation with clinical features than carotid angiography in this case of antiphospholipid syndrome leading to stroke.",

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AU - Sayama, Tetsuro

AU - Inamura, T.

AU - Morioka, T.

AU - Inoha, S.

AU - Nakamizo, A.

AU - Ikezaki, K.

AU - Matsushima, T.

AU - Sasaki, M.

AU - Fukui, M.

PY - 2001

Y1 - 2001

N2 - Angiography in a 35-year-old man, with a history of transient ischaemic attacks and a convulsive seizure, showed bilateral stenosis of the distal internal carotid arteries, and positron-emission tomography (PET) revealed inadequate blood flow in the right frontal lobe (decreased blood flow, increased oxygen extraction). A lupus anticoagulant and an elevated anticardiolipin antibody concentration were detected in serum. The patient's condition progressed from ischaemia to infarction resulting in the diagnosis of antiphospholipid syndrome and steroid and antiplatelet treatment resulted in an improved neurologic state and laboratory findings. PET showed better correlation with clinical features than carotid angiography in this case of antiphospholipid syndrome leading to stroke.

AB - Angiography in a 35-year-old man, with a history of transient ischaemic attacks and a convulsive seizure, showed bilateral stenosis of the distal internal carotid arteries, and positron-emission tomography (PET) revealed inadequate blood flow in the right frontal lobe (decreased blood flow, increased oxygen extraction). A lupus anticoagulant and an elevated anticardiolipin antibody concentration were detected in serum. The patient's condition progressed from ischaemia to infarction resulting in the diagnosis of antiphospholipid syndrome and steroid and antiplatelet treatment resulted in an improved neurologic state and laboratory findings. PET showed better correlation with clinical features than carotid angiography in this case of antiphospholipid syndrome leading to stroke.

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Positron-emission tomography in stroke associated with antiphospholipid syndrome

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