Possible steroid binding site common to adrenal cytochrome P-450scc and prostatic steroid binding protein

O. Gotoh, Y. Tagashira, Ken-Ichirou Morohashi, Y. Fujii-Kuriyama

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

By searching the entire PIR-protein-sequence data base, we have found that a dodecapeptide sequence in bovine adrenal cytochrome P-450scc is closely related to that in rat prostatic steroid binding protein. The two proteins belong to unrelated protein families, but both have steroids as substrates or ligands. Thus, the dodecapeptides may be important for substrate/ligand recognition in the individual proteins.

Original languageEnglish
Pages (from-to)8-10
Number of pages3
JournalFEBS Letters
Volume188
Issue number1
DOIs
Publication statusPublished - Aug 19 1985

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Prostatein
Cytochromes
Steroids
Binding Sites
Proteins
Ligands
Substrates
Rats
Databases

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

Possible steroid binding site common to adrenal cytochrome P-450scc and prostatic steroid binding protein. / Gotoh, O.; Tagashira, Y.; Morohashi, Ken-Ichirou; Fujii-Kuriyama, Y.

In: FEBS Letters, Vol. 188, No. 1, 19.08.1985, p. 8-10.

Research output: Contribution to journalArticle

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