TY - JOUR
T1 - Possible steroid binding site common to adrenal cytochrome P-450scc and prostatic steroid binding protein
AU - Gotoh, O.
AU - Tagashira, Y.
AU - Morohashi, K.
AU - Fujii-Kuriyama, Y.
N1 - Funding Information:
This work was partly supportedb y grantsf rom the Ministry of Education, Sciencea nd Culture of Japan.
PY - 1985/8/19
Y1 - 1985/8/19
N2 - By searching the entire PIR-protein-sequence data base, we have found that a dodecapeptide sequence in bovine adrenal cytochrome P-450scc is closely related to that in rat prostatic steroid binding protein. The two proteins belong to unrelated protein families, but both have steroids as substrates or ligands. Thus, the dodecapeptides may be important for substrate/ligand recognition in the individual proteins.
AB - By searching the entire PIR-protein-sequence data base, we have found that a dodecapeptide sequence in bovine adrenal cytochrome P-450scc is closely related to that in rat prostatic steroid binding protein. The two proteins belong to unrelated protein families, but both have steroids as substrates or ligands. Thus, the dodecapeptides may be important for substrate/ligand recognition in the individual proteins.
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U2 - 10.1016/0014-5793(85)80864-4
DO - 10.1016/0014-5793(85)80864-4
M3 - Article
C2 - 4040479
AN - SCOPUS:0022387771
SN - 0014-5793
VL - 188
SP - 8
EP - 10
JO - FEBS Letters
JF - FEBS Letters
IS - 1
ER -