A single EAG-active component was found in a pheromone extract from virgin females of the tussock moth, Orgyia postica. This compound named posticlure possesses a trans-epoxy ring and was identified as (6Z,9Z,11S,12S)-11,12-epoxyhenicosa-6,9-diene by means of GC-MS, 1H NMR and chiral HPLC analyses, and further chemical derivation followed by the GC-MS analysis. In a field test with the pheromone synthesized stereoselectivity, the male moths were specifically attracted to the (11S,12S)-isomer but not to the antipode.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry