Abstract
Ambient particulate matter 2.5 (PM2.5) is one of the main components of air pollutants, which can absorb many polycyclic aromatic hydrocarbons and metals. The effect of PM2.5 on human skin and its biological significance in skin homeostasis remain incompletely understood. Previous studies demonstrated that PM2.5 can activate aryl hydrocarbon receptor (AhR), generate reactive oxygen species, and induce skin inflammation. These processes may be involved in melanocyte homeostasis and melanogenesis. We hypothesize that AhR signaling may be responsible for PM2.5-related hyperpigmentation.
| Original language | English |
|---|---|
| Article number | 105063 |
| Journal | Environment International |
| Volume | 132 |
| DOIs | |
| Publication status | Published - Nov 2019 |
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All Science Journal Classification (ASJC) codes
- Environmental Science(all)
Cite this
Potential role of PM2.5 in melanogenesis. / Peng, Fen; Tsuji, Gaku; Zhang, Jian zhong; Chen, Zhou; Furue, Masutaka.
In: Environment International, Vol. 132, 105063, 11.2019.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Potential role of PM2.5 in melanogenesis
AU - Peng, Fen
AU - Tsuji, Gaku
AU - Zhang, Jian zhong
AU - Chen, Zhou
AU - Furue, Masutaka
PY - 2019/11
Y1 - 2019/11
N2 - Ambient particulate matter 2.5 (PM2.5) is one of the main components of air pollutants, which can absorb many polycyclic aromatic hydrocarbons and metals. The effect of PM2.5 on human skin and its biological significance in skin homeostasis remain incompletely understood. Previous studies demonstrated that PM2.5 can activate aryl hydrocarbon receptor (AhR), generate reactive oxygen species, and induce skin inflammation. These processes may be involved in melanocyte homeostasis and melanogenesis. We hypothesize that AhR signaling may be responsible for PM2.5-related hyperpigmentation.
AB - Ambient particulate matter 2.5 (PM2.5) is one of the main components of air pollutants, which can absorb many polycyclic aromatic hydrocarbons and metals. The effect of PM2.5 on human skin and its biological significance in skin homeostasis remain incompletely understood. Previous studies demonstrated that PM2.5 can activate aryl hydrocarbon receptor (AhR), generate reactive oxygen species, and induce skin inflammation. These processes may be involved in melanocyte homeostasis and melanogenesis. We hypothesize that AhR signaling may be responsible for PM2.5-related hyperpigmentation.
UR - http://www.scopus.com/inward/record.url?scp=85072546346&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85072546346&partnerID=8YFLogxK
U2 - 10.1016/j.envint.2019.105063
DO - 10.1016/j.envint.2019.105063
M3 - Review article
C2 - 31394397
AN - SCOPUS:85072546346
VL - 132
JO - Environmental International
JF - Environmental International
SN - 0160-4120
M1 - 105063
ER -