Potential role of PM2.5 in melanogenesis

Fen Peng; Gaku Tsuji; Jian zhong Zhang; Zhou Chen; Masutaka Furue

doi:10.1016/j.envint.2019.105063

Potential role of PM_2.5 in melanogenesis

Fen Peng, Gaku Tsuji, Jian zhong Zhang, Zhou Chen, Masutaka Furue

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Ambient particulate matter 2.5 (PM_2.5) is one of the main components of air pollutants, which can absorb many polycyclic aromatic hydrocarbons and metals. The effect of PM_2.5 on human skin and its biological significance in skin homeostasis remain incompletely understood. Previous studies demonstrated that PM_2.5 can activate aryl hydrocarbon receptor (AhR), generate reactive oxygen species, and induce skin inflammation. These processes may be involved in melanocyte homeostasis and melanogenesis. We hypothesize that AhR signaling may be responsible for PM_2.5-related hyperpigmentation.

Original language	English
Article number	105063
Journal	Environment International
Volume	132
DOIs	https://doi.org/10.1016/j.envint.2019.105063
Publication status	Published - Nov 2019

All Science Journal Classification (ASJC) codes

Environmental Science(all)

Access to Document

10.1016/j.envint.2019.105063

Fingerprint Dive into the research topics of 'Potential role of PM<sub>2.5</sub> in melanogenesis'. Together they form a unique fingerprint.

Cite this

@article{0b770ce76abb43cda179d54f48951fd8,

title = "Potential role of PM2.5 in melanogenesis",

abstract = "Ambient particulate matter 2.5 (PM2.5) is one of the main components of air pollutants, which can absorb many polycyclic aromatic hydrocarbons and metals. The effect of PM2.5 on human skin and its biological significance in skin homeostasis remain incompletely understood. Previous studies demonstrated that PM2.5 can activate aryl hydrocarbon receptor (AhR), generate reactive oxygen species, and induce skin inflammation. These processes may be involved in melanocyte homeostasis and melanogenesis. We hypothesize that AhR signaling may be responsible for PM2.5-related hyperpigmentation.",

author = "Fen Peng and Gaku Tsuji and Zhang, {Jian zhong} and Zhou Chen and Masutaka Furue",

year = "2019",

month = nov,

doi = "10.1016/j.envint.2019.105063",

language = "English",

volume = "132",

journal = "Environmental International",

issn = "0160-4120",

publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Potential role of PM2.5 in melanogenesis

AU - Peng, Fen

AU - Tsuji, Gaku

AU - Zhang, Jian zhong

AU - Chen, Zhou

AU - Furue, Masutaka

PY - 2019/11

Y1 - 2019/11

N2 - Ambient particulate matter 2.5 (PM2.5) is one of the main components of air pollutants, which can absorb many polycyclic aromatic hydrocarbons and metals. The effect of PM2.5 on human skin and its biological significance in skin homeostasis remain incompletely understood. Previous studies demonstrated that PM2.5 can activate aryl hydrocarbon receptor (AhR), generate reactive oxygen species, and induce skin inflammation. These processes may be involved in melanocyte homeostasis and melanogenesis. We hypothesize that AhR signaling may be responsible for PM2.5-related hyperpigmentation.

AB - Ambient particulate matter 2.5 (PM2.5) is one of the main components of air pollutants, which can absorb many polycyclic aromatic hydrocarbons and metals. The effect of PM2.5 on human skin and its biological significance in skin homeostasis remain incompletely understood. Previous studies demonstrated that PM2.5 can activate aryl hydrocarbon receptor (AhR), generate reactive oxygen species, and induce skin inflammation. These processes may be involved in melanocyte homeostasis and melanogenesis. We hypothesize that AhR signaling may be responsible for PM2.5-related hyperpigmentation.

UR - http://www.scopus.com/inward/record.url?scp=85072546346&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85072546346&partnerID=8YFLogxK

U2 - 10.1016/j.envint.2019.105063

DO - 10.1016/j.envint.2019.105063

M3 - Review article

C2 - 31394397

AN - SCOPUS:85072546346

VL - 132

JO - Environmental International

JF - Environmental International

SN - 0160-4120

M1 - 105063

ER -