Powerful actuation of magnetized microtools by focused magnetic field for particle sorting in a chip

Yoko Yamanishi, Shinya Sakuma, Kazuhisa Onda, Fumihito Arai

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

This paper describes a novel powerful noncontact actuation of a magnetically driven microtool (MMT), achieved by magnetization of the MMT and focusing of the magnetic field in a microfluidic chip for particle sorting. The following are the highlights of this study: (1) an MMT was successfully fabricated from a mixture of neodymium powder and polydimethylsiloxane; the MMT was magnetized such that it acted as an elastic micromagnet with a magnetic flux density that increased by about 100 times after magnetization, and (2) a pair of sharp magnetic needles was fabricated adjacent to a microchannel in a chip by electroplating, in order to focus the magnetic flux density generated by the electromagnetic coils below the biochip; these needles contribute to miniaturization of an actuation module that would enable the integration of multiple functions in the limited area of a chip. FEM analysis of the magnetic flux density around the MMT showed that the magnetic flux density in the setup with the magnetic needles was around 8 times better than that in the setup without the needles. By magnetization, the drive frequency of the MMT improved by about 10 times-from 18 Hz to 180 Hz. We successfully demonstrated the separation of copolymer beads of a particular size in a chip by image sensing.

Original languageEnglish
Pages (from-to)745-752
Number of pages8
JournalBiomedical Microdevices
Volume12
Issue number4
DOIs
Publication statusPublished - Aug 1 2010

Fingerprint

Magnetic flux
Magnetic Fields
Sorting
Needles
Magnetic fields
Magnetization
Electroplating
Miniaturization
Neodymium
Biochips
Microfluidics
Electromagnetic Phenomena
Polydimethylsiloxane
Microchannels
Powders
Copolymers
Finite element method

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Molecular Biology

Cite this

Powerful actuation of magnetized microtools by focused magnetic field for particle sorting in a chip. / Yamanishi, Yoko; Sakuma, Shinya; Onda, Kazuhisa; Arai, Fumihito.

In: Biomedical Microdevices, Vol. 12, No. 4, 01.08.2010, p. 745-752.

Research output: Contribution to journalArticle

Yamanishi, Yoko ; Sakuma, Shinya ; Onda, Kazuhisa ; Arai, Fumihito. / Powerful actuation of magnetized microtools by focused magnetic field for particle sorting in a chip. In: Biomedical Microdevices. 2010 ; Vol. 12, No. 4. pp. 745-752.
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