Precisely size controlled liposome formation with a microfluidic device

Mitsuru Shibata, Yukihiro Okamoto, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We greatly improved our previous liposome preparation method [1] in terms of the flow direction and liposome solvent, and could prepare precisely size controlled liposomes (97-139 nm in diameter) with narrow size distribution (2.9-6.5% CV) easily and rapidly, which cannot be attained with conventional bulk methods and our previous one. Liposomes with specific sizes and narrow size distribution would greatly enhance drug delivery and gene therapy efficacy.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages624-626
Number of pages3
ISBN (Print)9780979806421
Publication statusPublished - Jan 1 2009
Externally publishedYes
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: Nov 1 2009Nov 5 2009

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period11/1/0911/5/09

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Shibata, M., Okamoto, Y., Kaji, N., Tokeshi, M., & Baba, Y. (2009). Precisely size controlled liposome formation with a microfluidic device. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 624-626). Chemical and Biological Microsystems Society.