Prediction of improved liver function after balloon-occluded retrograde transvenous obliteration: Relation to hepatic vein pressure gradient

hideo uehara, Tomohiko Akahoshi, Morimasa Tomikawa, Nao Kinjo, Naotaka Hashimoto, Yoshihiro Nagao, Masahiro Kamori, Yoshihiko Maehara

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background and Aims: Balloon-occluded retrograde transvenous obliteration (B-RTO) is an effective treatment for gastric varices (GVx), as well as hepatic encephalopathy. The aim of this study was to examine the changes of the hepatic vein pressure gradient (HVPG) after B-RTO and determine the relation between the changes of HVPG and liver function. Patients and Methods: B-RTO was performed in 30 patients with GVx and hepatic encephalopathy. HVPG was measured in 19 of 30 patients both before and after B-RTO. Results: The B-RTO was successful in all patients. The GVx and hepatic encephalopathy were improved, and no recurrence or bleeding was observed within the follow- up period. The serum albumin and prothrombin activity were significantly improved 6months after B-RTO in all patients. HVPG was elevated 44% above the baseline after B-RTO. Liver function significantly improved 6months after B-RTO in patients whose HVPG increased≥20% from baseline. Conclusion: An elevated HVPG after B-RTO is one aspect of the effect of liver function, and an HVPG increase of≥20% from baseline is a predictive factor for obtaining an improvement of liver function.

Original languageEnglish
Pages (from-to)137-141
Number of pages5
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume27
Issue number1
DOIs
Publication statusPublished - Jan 1 2012

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Hepatic Veins
Pressure
Liver
Hepatic Encephalopathy
Esophageal and Gastric Varices
Prothrombin
Serum Albumin
Hemorrhage
Recurrence

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

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Prediction of improved liver function after balloon-occluded retrograde transvenous obliteration : Relation to hepatic vein pressure gradient. / uehara, hideo; Akahoshi, Tomohiko; Tomikawa, Morimasa; Kinjo, Nao; Hashimoto, Naotaka; Nagao, Yoshihiro; Kamori, Masahiro; Maehara, Yoshihiko.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 27, No. 1, 01.01.2012, p. 137-141.

Research output: Contribution to journalArticle

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AU - Kinjo, Nao

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AU - Kamori, Masahiro

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