Prediction of survival time after curative surgery for advanced gastric cancer

S. Moriguchi, Yoshihiko Maehara, D. Korenaga, K. Sugimachi, Y. Hayashi, Y. Nose

Research output: Contribution to journalArticle

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Abstract

This study was carried out to define independent prognostic factors influencing survival time and to examine the survival time of patients with advanced gastric cancer treated by curative resection. Six hundred and forty-eight patients were identified of whom 275 patients died of tumor recurrence during follow-up. Univariate analysis using Mantel-Cox analysis, indicated that tumor size, tumor location, gross appearance, degree of gastric wall invasion, lymph node metastasis and operative procedures were significant factors related to survival time (P < 0.01 to P < 0.05). Multivariate analysis using the Cox proportional hazard model adjusted for sex, age and other factors, suggested that tumor size (P < 0.01, relative risk = 1.79), degree of gastric wall invasion (P < 0.01, rr = 1.24) and lymph node metastasis (P < 0.01, rr = 2.39) were the most independent prognostic factors statistically, although these three prognostic factors were inter-related. When the tumor is less than 5 cm and there is no serosal invasion or lymph node metastasis, then a longer survival time can be expected (88.7% at 5-years). If the tumor size exceeds 10 cm and there is invasion into neighboring structures and lymph node metastases, then survival time will be short (11.9% at 4-years).

Original languageEnglish
Pages (from-to)287-292
Number of pages6
JournalEuropean Journal of Surgical Oncology
Volume18
Issue number3
Publication statusPublished - Jan 1 1992

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Stomach Neoplasms
Survival
Lymph Nodes
Neoplasm Metastasis
Neoplasms
Stomach
Age Factors
Operative Surgical Procedures
Proportional Hazards Models
Multivariate Analysis
Recurrence

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oncology

Cite this

Moriguchi, S., Maehara, Y., Korenaga, D., Sugimachi, K., Hayashi, Y., & Nose, Y. (1992). Prediction of survival time after curative surgery for advanced gastric cancer. European Journal of Surgical Oncology, 18(3), 287-292.

Prediction of survival time after curative surgery for advanced gastric cancer. / Moriguchi, S.; Maehara, Yoshihiko; Korenaga, D.; Sugimachi, K.; Hayashi, Y.; Nose, Y.

In: European Journal of Surgical Oncology, Vol. 18, No. 3, 01.01.1992, p. 287-292.

Research output: Contribution to journalArticle

Moriguchi, S, Maehara, Y, Korenaga, D, Sugimachi, K, Hayashi, Y & Nose, Y 1992, 'Prediction of survival time after curative surgery for advanced gastric cancer', European Journal of Surgical Oncology, vol. 18, no. 3, pp. 287-292.
Moriguchi S, Maehara Y, Korenaga D, Sugimachi K, Hayashi Y, Nose Y. Prediction of survival time after curative surgery for advanced gastric cancer. European Journal of Surgical Oncology. 1992 Jan 1;18(3):287-292.
Moriguchi, S. ; Maehara, Yoshihiko ; Korenaga, D. ; Sugimachi, K. ; Hayashi, Y. ; Nose, Y. / Prediction of survival time after curative surgery for advanced gastric cancer. In: European Journal of Surgical Oncology. 1992 ; Vol. 18, No. 3. pp. 287-292.
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