Predictors of lymph node metastasis in early gastric cancer

Y. Maehara, H. Orita, T. Okuyama, S. Moriguchi, S. Tsujitani, D. Korenaga, K. Sugimachi

Research output: Contribution to journalArticle

208 Citations (Scopus)

Abstract

Data were analysed on 396 patients with early gastric cancer who underwent resection in this department; special reference was made to lymph node metastasis. Metastases were present in the dissected lymph nodes of 47 patients (11.9 per cent). The survival rate for patients with metastasis to lymph nodes was lower than for those without such metastasis (P < 0.05). Lymph node metastasis was associated with larger tumour, a higher incidence of submucosal invasion, a higher rate of lymphatic vessel involvement, an advanced stage of disease and a non‐curative resection rate of 6.4 per cent. Multivariate analysis showed that the independent risk factors for lymph node metastasis in patients with early gastric cancer were large tumour size, lymphatic vessel involvement and invasion into the submucosal layer. In patients with these risk factors, lymph node dissection and postoperative adjuvant therapy should be performed in an attempt to prevent recurrence in the form of lymph node metastasis.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
JournalBritish Journal of Surgery
Volume79
Issue number3
DOIs
Publication statusPublished - Mar 1992

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Stomach Neoplasms
Lymph Nodes
Neoplasm Metastasis
Lymphatic Vessel Tumors
Lymphatic Vessels
Lymph Node Excision
Multivariate Analysis
Survival Rate
Recurrence
Incidence
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Maehara, Y., Orita, H., Okuyama, T., Moriguchi, S., Tsujitani, S., Korenaga, D., & Sugimachi, K. (1992). Predictors of lymph node metastasis in early gastric cancer. British Journal of Surgery, 79(3), 245-247. https://doi.org/10.1002/bjs.1800790320

Predictors of lymph node metastasis in early gastric cancer. / Maehara, Y.; Orita, H.; Okuyama, T.; Moriguchi, S.; Tsujitani, S.; Korenaga, D.; Sugimachi, K.

In: British Journal of Surgery, Vol. 79, No. 3, 03.1992, p. 245-247.

Research output: Contribution to journalArticle

Maehara, Y, Orita, H, Okuyama, T, Moriguchi, S, Tsujitani, S, Korenaga, D & Sugimachi, K 1992, 'Predictors of lymph node metastasis in early gastric cancer', British Journal of Surgery, vol. 79, no. 3, pp. 245-247. https://doi.org/10.1002/bjs.1800790320
Maehara Y, Orita H, Okuyama T, Moriguchi S, Tsujitani S, Korenaga D et al. Predictors of lymph node metastasis in early gastric cancer. British Journal of Surgery. 1992 Mar;79(3):245-247. https://doi.org/10.1002/bjs.1800790320
Maehara, Y. ; Orita, H. ; Okuyama, T. ; Moriguchi, S. ; Tsujitani, S. ; Korenaga, D. ; Sugimachi, K. / Predictors of lymph node metastasis in early gastric cancer. In: British Journal of Surgery. 1992 ; Vol. 79, No. 3. pp. 245-247.
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