Predictors of menstrual resumption by patients with anorexia nervosa

Chikako Arimura, T. Nozaki, S. Takakura, K. Kawai, M. Takii, N. Sudo, C. Kubo

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

OBJECTIVE: To investigate which factors predict the resumption of menstruation by patients with anorexia nervosa (AN). METHODS: Participants were AN patients who, even after weight recovery by inpatient treatment, had prolonged amenorrhea (N=11), AN patients who resumed menstruation after weight recovery (N=9), and age-matched healthy controls (N=12). Anthropometric data and the serum levels of leptin, insulin-like growth factor I (IGF-1), cortisol, luteinizing hormone (LH), estradiol (E2), and other hormones were measured at the beginning of the inpatient treatment and after weight recovery. RESULTS: Of the baseline anthropometric and hormonal factors, logistic regression analysis extracted a high serum cortisol level as a predictor of the inhibition of the resumption of menstruation. After weight recovery, the E 2 and leptin levels were significantly higher for eumenorrheic patients than for amenorrheic patients. CONCLUSION: The baseline serum cortisol level was a predictor of the prolonged inhibition of menstrual recovery.

Original languageEnglish
Pages (from-to)e226-e233
JournalEating and Weight Disorders
Volume15
Issue number4
DOIs
Publication statusPublished - Dec 1 2010

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Anorexia Nervosa
Menstruation
Hydrocortisone
Weights and Measures
Leptin
Insulin-Like Growth Factor I
Inpatients
Serum
Amenorrhea
Luteinizing Hormone
Estradiol
Logistic Models
Regression Analysis
Hormones
Therapeutics
Inhibition (Psychology)

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Predictors of menstrual resumption by patients with anorexia nervosa. / Arimura, Chikako; Nozaki, T.; Takakura, S.; Kawai, K.; Takii, M.; Sudo, N.; Kubo, C.

In: Eating and Weight Disorders, Vol. 15, No. 4, 01.12.2010, p. e226-e233.

Research output: Contribution to journalArticle

Arimura, Chikako ; Nozaki, T. ; Takakura, S. ; Kawai, K. ; Takii, M. ; Sudo, N. ; Kubo, C. / Predictors of menstrual resumption by patients with anorexia nervosa. In: Eating and Weight Disorders. 2010 ; Vol. 15, No. 4. pp. e226-e233.
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AU - Sudo, N.

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