Preload sensitivity in cardiac assist devices

Kiyotaka Fukamachi, Akira Shiose, Alex Massiello, David J. Horvath, Leonard A.R. Golding, Sangjin Lee, Randall C. Starling

Research output: Contribution to journalReview article

18 Citations (Scopus)

Abstract

With implantable cardiac assist devices increasingly proving their effectiveness as therapeutic options for end-stage heart failure, it is important for clinicians to understand the unique physiology of device-assisted circulation. Preload sensitivity as it relates to cardiac assist devices is derived from the Frank-Starling relationship between human ventricular filling pressures and ventricular stroke volume. In this review, we stratify the preload sensitivity of 17 implantable cardiac assist devices relative to the native heart and discuss the effect of preload sensitivity on left ventricular volume unloading, levels of cardiac support, and the future development of continuous-flow total artificial heart technology.

Original languageEnglish
Pages (from-to)373-380
Number of pages8
JournalAnnals of Thoracic Surgery
Volume95
Issue number1
DOIs
Publication statusPublished - Jan 1 2013
Externally publishedYes

Fingerprint

Equipment and Supplies
Assisted Circulation
Artificial Heart
Starlings
Ventricular Pressure
Stroke Volume
Heart Failure
Technology
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Fukamachi, K., Shiose, A., Massiello, A., Horvath, D. J., Golding, L. A. R., Lee, S., & Starling, R. C. (2013). Preload sensitivity in cardiac assist devices. Annals of Thoracic Surgery, 95(1), 373-380. https://doi.org/10.1016/j.athoracsur.2012.07.077

Preload sensitivity in cardiac assist devices. / Fukamachi, Kiyotaka; Shiose, Akira; Massiello, Alex; Horvath, David J.; Golding, Leonard A.R.; Lee, Sangjin; Starling, Randall C.

In: Annals of Thoracic Surgery, Vol. 95, No. 1, 01.01.2013, p. 373-380.

Research output: Contribution to journalReview article

Fukamachi, K, Shiose, A, Massiello, A, Horvath, DJ, Golding, LAR, Lee, S & Starling, RC 2013, 'Preload sensitivity in cardiac assist devices', Annals of Thoracic Surgery, vol. 95, no. 1, pp. 373-380. https://doi.org/10.1016/j.athoracsur.2012.07.077
Fukamachi K, Shiose A, Massiello A, Horvath DJ, Golding LAR, Lee S et al. Preload sensitivity in cardiac assist devices. Annals of Thoracic Surgery. 2013 Jan 1;95(1):373-380. https://doi.org/10.1016/j.athoracsur.2012.07.077
Fukamachi, Kiyotaka ; Shiose, Akira ; Massiello, Alex ; Horvath, David J. ; Golding, Leonard A.R. ; Lee, Sangjin ; Starling, Randall C. / Preload sensitivity in cardiac assist devices. In: Annals of Thoracic Surgery. 2013 ; Vol. 95, No. 1. pp. 373-380.
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