Prenatal diagnosis of periventricular venous infarction in utero: a case with hereditary protein C deficiency: A Case Report

Yuka Otera, Yasuo Yumoto, Masayuki Ochiai, Koji Yamashita, Kiyoko Kato

Research output: Contribution to journalArticlepeer-review

Abstract

A 36-year-old primigravida woman with a normal pregnancy course presented with fetal unilateral focal ventriculomegaly on routine ultrasonography performed at 28 weeks of gestation. Periventricular venous infarction (PVI) in utero was diagnosed with fetal magnetic resonance imaging (MRI). The neonate was born at term uneventfully and in utero PVI was confirmed by MRI after birth. The neonate was diagnosed with hereditary protein C deficiency after coagulation laboratory studies. At 10 months of age, the infant presented with mild retardation of motor development. This is the first report about prenatally diagnosed PVI in utero by fetal MRI. When focal, unilateral enlargement of the ventricles is detected in utero by prenatal ultrasonography, it is important to consider PVI and perform confirmatory fetal MRI.
Original languageEnglish
Number of pages4
JournalCase Reports in Perinatal Medicine
Volume4
Issue number2
Publication statusPublished - Sep 2015

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