Prenatal three-dimensional images of proximal focal femoral deficiency produced by helical computed tomography

Yuka Otera, Seiichi Morokuma, Yasuo Yumoto, Satoshi Hojo, Takako Gotoh, Toshiro Hara, Yasuhiro Ushijima, Yasuharu Nakashima, Kiyomi Tsukimori, Norio Wake

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5 Citations (Scopus)

Abstract

Introduction: Proximal focal femoral deficiency (PFFD) is a rare skeletal disorder characterized by failure in development of the subtrochanteric region of the femoral shaft, with varying degrees of shortening of the proximal femur. Objective: To investigate the potential of helical computed tomography as a prenatal diagnostic tool for bony abnormalities. Case: A 37-year-old Japanese woman was referred to our hospital at 32 weeks of gestation for the evaluation of fetal growth restriction with short femurs. An ultrasound examination revealed the fetus to have short femurs bilaterally with normal echogenicity, and a normal facial profile. Assessment by 3D CT confirmed the absence of the femoral heads bilaterally and also revealed bilateral hip dislocations and oligodactyly of the right hand. The baby was delivered by cesarean section at 37 weeks of gestation, whereupon the diagnosis of PFFD was confirmed. Conclusion: Helical CT is a useful prenatal diagnostic alternative for bony abnormalities that is superior to the conventional sonographic approach.

Original languageEnglish
Pages (from-to)349-353
Number of pages5
JournalFetal Diagnosis and Therapy
Volume25
Issue number3
DOIs
Publication statusPublished - Sep 1 2009

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All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Embryology
  • Radiology Nuclear Medicine and imaging
  • Obstetrics and Gynaecology

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