Preoperative therapy with insufficient effectiveness is related to unfavorable prognosis of patients with esophageal squamous cell carcinoma

Tadahiro Nozoe

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The disadvantage brought by the preoperative therapy with insufficient effectiveness for the patients with esophageal carcinoma has not been previously investigated. The aim of the current study was to show that the prognosis of patients with advanced esophageal carcinoma treated with preoperative therapy with insufficient effectiveness may be rather more unfavorable than that of patients without preoperative therapy. The subjects were 406 patients with esophageal squamous cell carcinomas of depth reaching to inuscitlaris propria or adventitia but not to neighboring structures, who had been treated with esophagectomy and reconstruction. Although the proportions of lymphatic invasion and venous invasion in patients treated with preoperative therapy of insufficient effect were lower than those of patients without preoperative therapy, the 1-, 3- and 5-year survival rates in the former (62.2%, 32.0% and 23.1%, respectively) was significantly lower than in the latter (78.5%, 57.3% and 39.7%, respectively, p=0.01). A preoperative therapy with insufficient effectiveness may bring a more unfavorable prognosis of patients with esophageal squamous cell carcinoma.

Original languageEnglish
Pages (from-to)1103-1106
Number of pages4
JournalOncology reports
Volume8
Issue number5
Publication statusPublished - Dec 1 2001

Fingerprint

Therapeutics
Carcinoma
Adventitia
Esophagectomy
Esophageal Squamous Cell Carcinoma
Survival Rate

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Preoperative therapy with insufficient effectiveness is related to unfavorable prognosis of patients with esophageal squamous cell carcinoma. / Nozoe, Tadahiro.

In: Oncology reports, Vol. 8, No. 5, 01.12.2001, p. 1103-1106.

Research output: Contribution to journalArticle

@article{aff7a7323d2f4abfa90b47a0a97aa89b,
title = "Preoperative therapy with insufficient effectiveness is related to unfavorable prognosis of patients with esophageal squamous cell carcinoma",
abstract = "The disadvantage brought by the preoperative therapy with insufficient effectiveness for the patients with esophageal carcinoma has not been previously investigated. The aim of the current study was to show that the prognosis of patients with advanced esophageal carcinoma treated with preoperative therapy with insufficient effectiveness may be rather more unfavorable than that of patients without preoperative therapy. The subjects were 406 patients with esophageal squamous cell carcinomas of depth reaching to inuscitlaris propria or adventitia but not to neighboring structures, who had been treated with esophagectomy and reconstruction. Although the proportions of lymphatic invasion and venous invasion in patients treated with preoperative therapy of insufficient effect were lower than those of patients without preoperative therapy, the 1-, 3- and 5-year survival rates in the former (62.2{\%}, 32.0{\%} and 23.1{\%}, respectively) was significantly lower than in the latter (78.5{\%}, 57.3{\%} and 39.7{\%}, respectively, p=0.01). A preoperative therapy with insufficient effectiveness may bring a more unfavorable prognosis of patients with esophageal squamous cell carcinoma.",
author = "Tadahiro Nozoe",
year = "2001",
month = "12",
day = "1",
language = "English",
volume = "8",
pages = "1103--1106",
journal = "Oncology Reports",
issn = "1021-335X",
publisher = "Spandidos Publications",
number = "5",

}

TY - JOUR

T1 - Preoperative therapy with insufficient effectiveness is related to unfavorable prognosis of patients with esophageal squamous cell carcinoma

AU - Nozoe, Tadahiro

PY - 2001/12/1

Y1 - 2001/12/1

N2 - The disadvantage brought by the preoperative therapy with insufficient effectiveness for the patients with esophageal carcinoma has not been previously investigated. The aim of the current study was to show that the prognosis of patients with advanced esophageal carcinoma treated with preoperative therapy with insufficient effectiveness may be rather more unfavorable than that of patients without preoperative therapy. The subjects were 406 patients with esophageal squamous cell carcinomas of depth reaching to inuscitlaris propria or adventitia but not to neighboring structures, who had been treated with esophagectomy and reconstruction. Although the proportions of lymphatic invasion and venous invasion in patients treated with preoperative therapy of insufficient effect were lower than those of patients without preoperative therapy, the 1-, 3- and 5-year survival rates in the former (62.2%, 32.0% and 23.1%, respectively) was significantly lower than in the latter (78.5%, 57.3% and 39.7%, respectively, p=0.01). A preoperative therapy with insufficient effectiveness may bring a more unfavorable prognosis of patients with esophageal squamous cell carcinoma.

AB - The disadvantage brought by the preoperative therapy with insufficient effectiveness for the patients with esophageal carcinoma has not been previously investigated. The aim of the current study was to show that the prognosis of patients with advanced esophageal carcinoma treated with preoperative therapy with insufficient effectiveness may be rather more unfavorable than that of patients without preoperative therapy. The subjects were 406 patients with esophageal squamous cell carcinomas of depth reaching to inuscitlaris propria or adventitia but not to neighboring structures, who had been treated with esophagectomy and reconstruction. Although the proportions of lymphatic invasion and venous invasion in patients treated with preoperative therapy of insufficient effect were lower than those of patients without preoperative therapy, the 1-, 3- and 5-year survival rates in the former (62.2%, 32.0% and 23.1%, respectively) was significantly lower than in the latter (78.5%, 57.3% and 39.7%, respectively, p=0.01). A preoperative therapy with insufficient effectiveness may bring a more unfavorable prognosis of patients with esophageal squamous cell carcinoma.

UR - http://www.scopus.com/inward/record.url?scp=0035461319&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035461319&partnerID=8YFLogxK

M3 - Article

C2 - 11496324

AN - SCOPUS:0035461319

VL - 8

SP - 1103

EP - 1106

JO - Oncology Reports

JF - Oncology Reports

SN - 1021-335X

IS - 5

ER -