Preparation and biological properties of saccharide-modified gold nanoparticles

Masayuki Toyoshima; Ken Ooya; Yoshiko Miura; Kazukiyo Kobayashi

doi:10.2497/jjspm.54.843

Preparation and biological properties of saccharide-modified gold nanoparticles

Masayuki Toyoshima, Ken Ooya, Yoshiko Miura, Kazukiyo Kobayashi

Research output: Contribution to journal › Article › peer-review

Abstract

The gold nanoparticels were modified by biological active saccharides, and the properties of gold nanoparticle including protein recognition abilities were investigated. First, the gold nanoparticle with a diameter of about 8 nm was modified by lactose-substituted mercapto oligoethylene. The gold nanoparticle was water soluble, and aggregated by addition of the specific recognition lectin. Then, the gold nanoparticle with a diameter of 40 nm was prepared by glycopolymer cattying α-mannoside. The gold nanoparticle with mannose was readily water soluble, and showed pink colour. The UV-adsorption of the gold nanoparticle was increased by addition of the specific recognition lectin of Concanavalin A though other protein didn't change the UV spectra.

Original language	English
Pages (from-to)	843-848
Number of pages	6
Journal	Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy
Volume	54
Issue number	12
DOIs	https://doi.org/10.2497/jjspm.54.843
Publication status	Published - Dec 2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Mechanical Engineering
Industrial and Manufacturing Engineering
Metals and Alloys
Materials Chemistry

Access to Document

10.2497/jjspm.54.843

Cite this

@article{b745e00eeb0742398e1a719f7afae915,

title = "Preparation and biological properties of saccharide-modified gold nanoparticles",

abstract = "The gold nanoparticels were modified by biological active saccharides, and the properties of gold nanoparticle including protein recognition abilities were investigated. First, the gold nanoparticle with a diameter of about 8 nm was modified by lactose-substituted mercapto oligoethylene. The gold nanoparticle was water soluble, and aggregated by addition of the specific recognition lectin. Then, the gold nanoparticle with a diameter of 40 nm was prepared by glycopolymer cattying α-mannoside. The gold nanoparticle with mannose was readily water soluble, and showed pink colour. The UV-adsorption of the gold nanoparticle was increased by addition of the specific recognition lectin of Concanavalin A though other protein didn't change the UV spectra.",

author = "Masayuki Toyoshima and Ken Ooya and Yoshiko Miura and Kazukiyo Kobayashi",

year = "2007",

month = dec,

doi = "10.2497/jjspm.54.843",

language = "English",

volume = "54",

pages = "843--848",

journal = "Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy",

issn = "0532-8799",

publisher = "Japan Society of Powder and Powder Metallurgy",

number = "12",

}

TY - JOUR

T1 - Preparation and biological properties of saccharide-modified gold nanoparticles

AU - Toyoshima, Masayuki

AU - Ooya, Ken

AU - Miura, Yoshiko

AU - Kobayashi, Kazukiyo

PY - 2007/12

Y1 - 2007/12

N2 - The gold nanoparticels were modified by biological active saccharides, and the properties of gold nanoparticle including protein recognition abilities were investigated. First, the gold nanoparticle with a diameter of about 8 nm was modified by lactose-substituted mercapto oligoethylene. The gold nanoparticle was water soluble, and aggregated by addition of the specific recognition lectin. Then, the gold nanoparticle with a diameter of 40 nm was prepared by glycopolymer cattying α-mannoside. The gold nanoparticle with mannose was readily water soluble, and showed pink colour. The UV-adsorption of the gold nanoparticle was increased by addition of the specific recognition lectin of Concanavalin A though other protein didn't change the UV spectra.

AB - The gold nanoparticels were modified by biological active saccharides, and the properties of gold nanoparticle including protein recognition abilities were investigated. First, the gold nanoparticle with a diameter of about 8 nm was modified by lactose-substituted mercapto oligoethylene. The gold nanoparticle was water soluble, and aggregated by addition of the specific recognition lectin. Then, the gold nanoparticle with a diameter of 40 nm was prepared by glycopolymer cattying α-mannoside. The gold nanoparticle with mannose was readily water soluble, and showed pink colour. The UV-adsorption of the gold nanoparticle was increased by addition of the specific recognition lectin of Concanavalin A though other protein didn't change the UV spectra.

UR - http://www.scopus.com/inward/record.url?scp=39749120646&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=39749120646&partnerID=8YFLogxK

U2 - 10.2497/jjspm.54.843

DO - 10.2497/jjspm.54.843

M3 - Article

AN - SCOPUS:39749120646

VL - 54

SP - 843

EP - 848

JO - Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy

JF - Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy

SN - 0532-8799

IS - 12

ER -

Preparation and biological properties of saccharide-modified gold nanoparticles

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this