Preparation and evaluation of o/w emulsions with an anionic lipid, containing lipophilic drug

Shunsuke Inenaga, Keitaro Sou, Shinji Takeoka, Eishun Tsuchida

Research output: Contribution to conferencePaperpeer-review

Abstract

The purpose of this study is efficient delivery of lipophilic drug such as curcumin using pharmacokinetics of nanoparticles with anionic lipid (L-Glutamic acid-N-(3-carboxyl-1-oxopropyl)-1,5-dihexadecyl ester (DHSG)). The o/w emulsions with (DMPC/DHSG/PEG-DSPE: 10/1/0.06 molar ratio) were prepared. We incorporated curcumin, into the emulsions and evaluated them. Furthermore, the organ distribution of the resulting emulsions was investigated to evaluate the pharmacokinetics in rats.

Original languageEnglish
Pages4866
Number of pages1
Publication statusPublished - 2006
Externally publishedYes
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: Sep 20 2006Sep 22 2006

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
Country/TerritoryJapan
CityToyama
Period9/20/069/22/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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