The purpose of this study is efficient delivery of lipophilic drug such as curcumin using pharmacokinetics of nanoparticles with anionic lipid (L-Glutamic acid-N-(3-carboxyl-1-oxopropyl)-1,5-dihexadecyl ester (DHSG)). The o/w emulsions with (DMPC/DHSG/PEG-DSPE: 10/1/0.06 molar ratio) were prepared. We incorporated curcumin, into the emulsions and evaluated them. Furthermore, the organ distribution of the resulting emulsions was investigated to evaluate the pharmacokinetics in rats.
|Number of pages||1|
|Publication status||Published - 2006|
|Event||55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan|
Duration: Sep 20 2006 → Sep 22 2006
|Other||55th Society of Polymer Science Japan Symposium on Macromolecules|
|Period||9/20/06 → 9/22/06|
All Science Journal Classification (ASJC) codes